Expert Discussion: Role of Pharmacists in Expanding Access to CAR T Therapies Without REMS
July 22nd 2025Debra Patt, MD, PhD, MBA, and Houston Holmes, MD, explore how the removal of risk evaluation and management strategies (REMS) for chimeric antigen receptor (CAR) T-cell (CAR T) therapies can improve health equity, expand access in community settings, and elevate the pharmacist’s role in care coordination.
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EHA 2025: No Added Toxicity Observed With Bleximenib Plus Venetoclax and Azacitidine in AML
July 22nd 2025Andrew H. Wei, PhD, discusses phase 1b findings on the safety, pharmacokinetics, and preliminary efficacy of combining the menin inhibitor bleximenib with venetoclax and azacitidine in patients with newly diagnosed or relapsed/refractory acute myeloid leukemia (AML) harboring NPM1 mutations or KMT2A rearrangements.
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The Impact of Pharmacist-Managed Insulin Therapy in the Intensive Care Unit
Critically ill patients treated with a pharmacist-managed insulin protocol achieved higher rates of glucose control than those treated with conventional methods.
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AACP 2025: From Research to Action on Representation Gaps in Pharmacy Education
July 21st 2025Omolola (Lola) Adeoye-Olatunde, PharmD, MS, discusses findings from a multi-year analysis of American Association of Colleges of Pharmacy (AACP) institutional data on faculty and graduate student representation in pharmacy education, highlighting persistent disparities and offering actionable strategies to improve equity and inclusion in the academic pipeline.
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ASCO 2025: Stratifying NSCLC Treatment by HER2-Alteration Subtype
Nikita Dahake, MD; Hossein Borghaei, DO, MS; and Yasmine Baca, MS, PhD candidate, MB(ASCP)CM, explore how distinct HER2-alteration subtypes in non-small cell lung cancer (NSCLC) impact survival outcomes, co-mutation profiles, and treatment response to immunotherapy-based regimens.
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EHA 2025: BMS-986458 Shows Clinical Promise in FL and DLBCL
July 21st 2025Franck Morschhauser, MD, PhD, discusses the novel cereblon-dependent bifunctional degrader BMS-986458, highlighting its selective targeting of BCL6, promising early efficacy in relapsed/refractory lymphoma, favorable safety profile, and future potential in combination regimens and earlier treatment lines.
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Hypertension: A Silent Killer Requiring Novel Therapies
Hypertension is widespread and linked to serious health risks, but new treatments for resistant cases target new mechanisms of action.
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FDA Panel Rejects Belantamab Mafodotin Combinations for Multiple Myeloma, Citing Safety Concerns
July 18th 2025The advisory committee cited concerns around ocular toxicity and overall tolerability, raising serious questions about the drug's benefit-risk profile ahead of its scheduled Prescription Drug User Fee Act action date on July 23, 2025.
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