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The application is based on positive results from the ASCEND phase 3 clinical trial, assessing the efficacy and safety of daprodustat for the treatment of anemia from chronic kidney disease.

FDA Accepts New Drug Application for Daprodustat as Treatment for Anemia, Chronic Kidney Disease

Recent studies demonstrated that renal failure, proteinuria, and histologic renal lesions can be prevented by mineralocorticoid receptor antagonists.

How Finerenone Compares to Other Mineralocorticoid Receptor Antagonists 

Despite their lower antibody responses, patients who are vaccinated receive protection from SARS-CoV-2 infection and severe disease.

COVID-19 Vaccination Protects Adults on Dialysis, Study Results Show

Trial of empagliflozin (Jardiance) in adults with chronic kidney disease will end early based on a recommendation from the trial’s Independent Data Monitoring Committee based on clear positive efficacy.

Boehringer Ingelheim, Lilly Halt Jardiance Chronic Kidney Disease Phase 3 Trial, Citing Positive Results

The FDA has approved Difelikefalin injection (Korsuva; Cara Therapeutics and Vifor Pharma) for the treatment of moderate-to-severe chronic kidney disease–associated pruritus in adults undergoing hemodialysis.

Korsuva From Cara Therapeutics and Vifor Pharma

Finerenone (Kerendia) is indicated to reduce the risk of sustained eGFR decline, end stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease.

Daily Medication Pearl: Finerenone (Kerendia)

Women had lower health-related quality of life at the beginning of the study, although men experienced a more rapid decline over time.

Health-Related Quality of Life Varies Between Men, Women With Advanced Kidney Disease

Severe or prolonged inflammation associated with glomerulonephritis can damage the kidneys. 

Pharmacy Clinical Pearl of the Day: Glomerulonephritis

New research raises concerns about the commonly prescribed medications used to treat heart failure and high blood pressure, though investigators say patients should continue to take them.

Long-Term Use of ACE Inhibitors May Cause Kidney Damage, Study Results Suggest

A survey was administered electronically to key kidney care stakeholders in 182 International Society of Nephrology (ISN)-affiliated countries, with 88% responding and 97% answering the survey items related to kidney nutrition care.

Study: Limited Global Availability of Nutrition-Related Care for Patients with Kidney Disease

® Chronic Kidney Disease Resource Center is a comprehensive resource for clinical news and expert insights on issues related to long-term disease of the kidneys leading to renal failure.