Examining Elafibranor as a Treatment Option for PBC
January 1st 2025Panelists discuss how elafibranor demonstrated significant efficacy in the ELATIVE trial, which strengthens confidence in its role as a long-term treatment option for patients with primary biliary cholangitis (PBC) who inadequately respond to ursodeoxycholic acid.
Improving Transitions of Care for Patients Receiving Bispecific Therapies and Final Recommendations
December 30th 2024Panelists discuss how key recommendations for optimizing bispecific therapy care focus on establishing robust communication protocols between academic and community centers while ensuring community centers develop comprehensive infrastructure including staff training, emergency protocols, and care coordination pathways.
Administering Bispecifics in the Community vs Academic Centers
December 30th 2024Panelists discuss understanding the comparative advantages, decision-making factors, infrastructure requirements, and partnership models for administering bispecific antibodies in community vs academic settings, with particular focus on patient care logistics and referral pathways.
Exploring Second-Line Treatments for PBC
December 25th 2024Panelists discuss how some patients with primary biliary cholangitis (PBC) have an inadequate response to ursodeoxycholic acid and require second-line treatments, with options including obeticholic acid, seladelpar, and elafibranor, which improve bile acid homeostasis and reduce inflammation.
Treatment Goals for Patients With PBC
December 25th 2024Panelists discuss how the main treatment goals for patients with primary biliary cholangitis (PBC) include improving liver biochemistry, preventing disease progression to cirrhosis, managing symptoms, and enhancing overall quality of life through regular monitoring and appropriate therapeutic interventions.
Navigating REMS Requirements and Educating Other Stakeholders on Bispecific Therapies
December 23rd 2024Panelists discuss the guidance on managing REMS program compliance for bispecific therapies and strategies for educating non-oncology health care providers about cytokine release syndrome (CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS) toxicities.
Infection Prevention and Leveraging EHR for Bispecific Therapy Management
December 23rd 2024Panelists discuss insights on infection prevention protocols and electronic health record (EHR)–based toxicity management strategies for patients receiving bispecific antibody therapies in relapsed/refractory multiple myeloma (RRMM).
Examining the 505(b)(2) Pathway and Implementation into EHR
December 20th 2024A panelist discusses how the 505(b)(2) regulatory pathway provides a streamlined approval process for modified versions of previously approved drugs, allowing pharmaceutical companies to rely partly on existing safety/efficacy data while still requiring new clinical data, commonly used across various therapeutic areas including reformulations, new dosage forms, and drug combinations.
Important Background Information on RSV for Pharmacists
December 20th 2024Traci M. Poole, PharmD, BCACP, BCGP, discusses the pathophysiology of respiratory syncytial virus (RSV) and its key complications, identifies high-risk populations for severe RSV infection, and explores best practices for recognizing these patients and ensuring they receive timely vaccination to prevent serious outcomes.
Public Health Matters Video: The Importance of Reproductive Justice and Black Maternal Health
December 19th 2024In this episode of Public Health Matters, Christina Madison discusses the concept of reproductive justice and ensuring Black maternal health efforts are not left behind with Regina Davis Moss of In Our Own Voice.