V116 is a novel 21-valent pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease and pneumococcal pneumonia.
Genome sequencing shows the clonality of outbreak isolates within each of 6 classes, which confirmed that recent transmissions accounted for high carriage.
Vaxneuvance was previously granted FDA Priority Review and Breakthrough Therapy designation for the prevention of invasive pneumococcal disease.
Electronic, open loop, clinical decision support system helped to produce a 38% lower overall mortality rate among patients with pneumonia.
The global impact of GBS causes approximately 150,000 deaths of babies each year.
The proof-of-concept study is expected to announce topline safety, tolerability, and immunogenicity results by the end of 2022.
Study shows there is no association between strep throat infection and the development of tics in children with a parent or sibling with a chronic tic disorder.
How would you respond to these patient questions?
Group B strep can cause dangerous infections in adults with certain chronic medical conditions.
The analysis of 204 countries and territories reveals that AMR is now a leading cause of death worldwide, which is higher than HIV/AIDS or malaria.
One viral protein could provide information to deter pneumonia causing the body’s exaggerated inflammatory response, new study results show.
The findings could help clinicians tailor the use of early antibiotics in newborns because only infants deemed at risk for infection should receive antibiotics.
Responses elicited by the pneumococcal vaccine for all 20 serotypes were similar whether administered with the COVID-19 vaccine or with placebo.
Lefamulin (Xenleta, Nabriva Therapeutics) is approved for the treatment of adults with community-acquired bacterial pneumonia caused by susceptible microorganisms.
The research team looked at a pooled analysis of all published studies to re-evaluate the relationship between regular exercise and the risk of developing pneumonia.
Chronic hypersensitivity pneumonitis is a long-term lung condition in which the interstitial tissue surrounding the alveoli of the lungs becomes inflamed and develops fibrosis.
Serotypes 22F, 33F, and 3 represent more than a quarter of invasive pneumococcal disease in children under the age of 5
Multiple GBS vaccine candidates are in development, but none are available despite development efforts spanning multiple decades.
AzaSite is indicated for the treatment of bacterial conjunctivitis caused by CDC coryneform group G, Haemophilus influenzae, Staphylococcus aureus, Streptococcus mitis group, and Streptococcus pneumoniae.
It was previously known that beta-lactam antibiotics function by restricting cell wall growth, but the exact mechanics have remained unknown until now.
Study of human lung tissue and airway samples from patients with bacterial pneumonia shows that IL-26 applies modulatory effects on the immune system.
This research could help improve the efficacy of antibiotics without clinicians having to attempt risky strategies such as providing patients with higher doses or relying on the discovery of new types of antibiotics, according to the study authors.
The study also found that certain E. coli cells in these microenvironments were able to survive phage treatment without acquiring genetic resistance.
The immune response of all 15 serotypes in the V114 pneumococcal vaccination were higher than those in the PCV13 vaccination.
Musey addressed any gaps and limitations that researchers should be focusing on in future studies and what he hopes to see for the future of pneumococcal vaccines and this disease.
