CLINICAL ROLE -
Replacing Brand-Name Cardiovascular Drugs Could Save Patients Money
New analysis shows the substitution would cut costs by $600 million in the United States annually.
Waldenström Macroglobulinemia: Common Presentations, Treatment Strategies
The uncommon disease shares features of both lymphoma and myeloma.
RPM Is Effective for Patients With Cancer During the Pandemic
The results of a pilot program investigating the efficacy of remote patient monitoring for patients with cancer showed that it helped to keep high-risk individuals out of the hospital.
FDA Approves Magnesium Sulfate Injection From Milla Pharmaceuticals
Agency green light could help get medication off ASHP drug shortage list by reducing supply issues.
Nasal Vaccines May Provide Additional Immune Support Against Respiratory Viruses
Immune B cells secrete immunoglobin A antibodies that work on mucosal surfaces in the nose, stomach, and lungs.
Immune Cell Population Potentially Responsible for Inflammation in Multiple Sclerosis
Inhibiting the activity of group 3 innate lymphoid cells could serve as a new therapeutic approach for neurologic conditions.
Researchers Develop New, More Accurate Assessment of Viral Exposure in a Population
Study predicts the future of antibody testing may move toward technologically advanced platforms that can test for multiple antibody types in a single blood sample.
Antihistamines Associated With Improved Immunotherapy Response in Patients With Cancer
Commonly used medications may influence responses to checkpoint inhibitors among patients with cancer.
Representation in Oncology Drug Trials Impacts Patient Health
The FDA looks to address a lack of diversity in cancer drug trials.
COVID-19-Related Stress Associated With Poorer Cognitive Ability, Risk-Taking Behavior
Study indicates those who experienced a greater amount of stress from the COVID-19 pandemic had reduced information processing speed.
Study: Prognosis of Chronic Hypersensitivity Pneumonitis Linked to Genetic Variations
Chronic hypersensitivity pneumonitis is a long-term lung condition in which the interstitial tissue surrounding the alveoli of the lungs becomes inflamed and develops fibrosis.
Patients Treated for Opioid Overdose Rarely Prescribed Naloxone, Buprenorphine
Study suggests that emergency physicians prescribe naloxone to patients who overdose.
Tracking Potential Triggers May Reduce Number of Episodes for Patients With Atrial Fibrillation
Common triggers for atrial fibrillation include alcohol, caffeine, and less sleep.
COVID-19 Vaccination Rates Among Individuals With HIV Vary By Geography
Immunocompromised individuals are at a higher risk of developing severe symptoms and dying from COVID-19.
Marginal Zone Lymphoma: Subtypes, Treatments, the Role of the Pharmacist
Although marginal zone lymphoma is relatively rare, it contains a broad spectrum of conditions under it that require an individualized treatment selection process.
Certain Patients With Blood Disorders Do Not Produce Antibodies Following COVID-19 Vaccination
Study may help guide COVID-19 vaccination strategies for patients with blood disorders.
Study Identifies Potential Drug Target for Depression, Anxiety
Researchers to explore possible approaches for designing small molecule therapeutics to combat depression.
Moderna COVID-19 Vaccine Effective Against Viral Variants, Delta Protection Wanes Over Time
Study shows moderately reduced efficacy of the Moderna COVID-19 vaccine over time against Delta infection, which supports current booster dose recommendations.
Studies Suggest Cannabinoid Metabolites Result in Harmful Drug Interactions
Major metabolites for cannabinoids may interfere with two families of enzymes that help metabolize a wide range of drugs prescribed for a variety of conditions.
Phase 3 Trial to Evaluate IVIG, Aspirin, Prednisolone Combination Therapy in Patients With Kawasaki Disease
Trial seeks to provide high-level evidence for improving the initial treatment for acute Kawasaki disease.
Preliminary Data Suggest GSK, Sanofi COVID-19 Booster Effective Regardless of Initial Vaccine
A single booster dose of the GlaxoSmithKline and Sanofi recombinant adjuvanted COVID-19 vaccine candidate delivered consistent and strong immune responses.
Experimental Gel Could Improve Arteriovenous Fistula Formation for Patients Requiring Hemodialysis
Up to 60% of arteriovenous fistulas fail to develop properly due to smooth muscle cell hyperplasia.
Early Switch to Fulvestrant, Palbocilib Combination Therapy May Provide Benefit to Certain Patients With Breast Cancer
Patients with hormone receptor-positive breast cancer doubled their median progression-free survival following a switch to fulvestrant plus palbociclib.
Pyrotinib Associated With Overall Survival Benefit for Certain Patients With Breast Cancer
Patients with breast cancer treated with pyrotinib plus capecitabine had a 31% lower risk of death than those treated with lapatinib and capecitabine
New Technique May Predict Response to Neoadjuvant Immunotherapy in Certain Patients With Breast Cancer
New technology provides information on the benefit of adding atezolizumab to chemotherapy as a neoadjuvant treatment for patients with early high-risk and locally advanced triple-negative breast cancer.
Expert Panel Reviews Recommended Therapy Options for Hodgkin Lymphoma
Experts reviewed the efficacy and safety of the recommended treatment regimens and discussed which treatment strategy they would recommend for their patients.
Certain Patients With Myelodysplastic Syndromes, Acute Leukemia at Higher Risk of Severe COVID-19 Illness
However, active disease alone for hospitalized patients was not associated with greater odds of dying from COVID-19, nor was receiving ongoing cancer treatment.
PI3K Inhibitors May Help Prevent Tamoxifen-Associated Uterine Cancer in Patients With Breast Cancer
Uterine cancers that developed in patients with breast cancer treated with tamoxifen had fewer phosphoinositol-3-kinase (PI3K) pathway mutations and may have been driven by tamoxifen-induced PI3K pathway activation.
Hemlibra Demonstrates Efficacy, Safety in Patients With Mild, Moderate Hemophilia A
Emicizumab-kxwh demonstrated a favorable safety profile and effective bleed control in people with mild or moderate hemophilia A without factor VIII inhibitors.
New Treatments Needed for Patients With Triple-Class Refractory Multiple Myeloma
The study demonstrates a need for novel tolerable and efficacious therapeutic agents to address the burden of illness in patients with multiple myeloma, according to the investigators.
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