Skin Cancer

High-risk areas for disease progression include genitalia and the scalp.

Each therapy presents a different but effective treatment option.

Novel drug development has been focused on the augmentation of the T-lymphocyte response.

Several studies have noted a potential link between methotrexate and an increased risk of skin cancer.

Merck and Moderna’s adjuvant melanoma treatment shows reduced risk of recurrence or death by 44% compared with pembrolizumab alone.

UC Davis cancer researchers hope new technology will help diagnose and treat melanoma more successfully.

Strengthening partnerships with healthcare professionals and driving awareness on the clinical benefits of dermatological skincare is the key to success in the public health space.

Sonidegib binds to and inhibits a transmembrane protein to disrupt hedgehog pathway signal transduction and leading to antitumor activity in patients with locally advanced basal cell carcinoma.

A researcher suggests that novel immune modulating cancer therapies like cancer vaccines can be more effective and safer alternative to previous cancer immunotherapies.

An integrative efficacy score would incorporate the depth, duration, and prevalence of tumor response.

KIN-2787 is a potential treatment for BRAF class II or III alteration-positive and/or NRAS mutation-positive, metastatic or unresectable, stage IIB to IV malignant melanoma.

Nivolumab is a biomarker that has been shown to benefit the survival of patients with stage 2 melanoma patients compared with placebo.

New research presented at ESMO Congress found that certain patients with advanced melanoma administered a combination of cemiplimab with fianlimab experienced a median progression-free survival of 2 years.

Joanna discusses her recommendations for sunscreen and what pharmacists picked as their favorite sunscreen product in the OTC Guide.

With the vast number of drugs that can induce photosensitivity, patients taking any of these medications should receive safety counseling, especially during the summer months.

Sonidegib is a biphenyl carboxamide that blocks the signaling in the hedgehog pathway.

Combination therapy with both nivolumab and relatlimab leads to increased T-cell activation compared with monotherapy with either agent alone.

Analysis included a 29% objective response rate in cohort 4 of the C-144-01 study, the company says.

Trametinib (Mekinist) is a kinase inhibitor indicated as a single agent for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA-approved test.

Because of the likelihood that patients with melanoma will develop adverse effects on therapy, it is crucial for pharmacists to proactively educate patients and provide them with tools to help mitigate and manage these issues.

Vusolimogene oderparepvec is in development for the treatment of multiple skin cancers either alone or in combination with anti-PD1 therapy.

The FDA previously granted Fast Track Designation for the combination of lifileucel and pembrolizumab in metastatic melanoma.

Cutaneous squamous cell carcinoma should be diagnosed early and treated promptly to avoid complications.

Relatlimab plus nivolumab (Opdualag) shows improved progression-free survival compared with nivolumab monotherapy in patients with unresectable or metastatic melanoma.

Kimmtrak found to be the first therapy to demonstrate a survival benefit for HLA-A*02:01–positive adult patients with unresectable or metastatic uveal melanoma.