CLINICAL ROLE -
Oncology Overview: Pirtobrutinib—A New BTK Inhibitor
Pirtobrutinib is under investigation in clinical trials in patients with CLL/small lymphocytic lymphoma, mantle cell lymphoma, and non-Hodgkin lymphoma.
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Clinical Overview: Glucarpidase (Voraxaze) for Methotrexate Toxicity
Methotrexate is an immunosuppressive agent used to treat cancer, dermatology-, and rheumatology-related issues.
Oncology Overview: Sonidegib (Odomzo) for Locally Advanced Basal Cell Carcinoma
Sonidegib is a biphenyl carboxamide that blocks the signaling in the hedgehog pathway.
Clinical Overview: Sacubitril/Valsartan (Entresto) for Chronic Heart Failure
Sacubitril/valsartan (Entresto)reduces the risk of hospitalization and death related to cardiovascular complications in patients with heart failure.
Clinical Overview: Evusheld for Pre-Exposure Prophylaxis of COVID-19
Evusheld has been found to significantly reduce the risk of developing symptomatic COVID-19.