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A stem cell with prominent nucleus and vesicles represents regeneration potential cellular therapy and the promise of personalized medicine and tissue engineering. | Image Credit: kaliel | stock.adobe.com

Chronic graft-vs-host disease (cGVHD) is the leading cause of late, non-relapse mortality for patients who have undergone an allogeneic hematopoietic stem cell transplant. Axatilimab, which has durable responses and an attractive safety profile, offers a novel mechanism of action for the treatment for patients who have not succeeded with at least 2 prior lines of systemic therapy.