Specialty Pharmacy

Backed by positive results in multiple clinical trials, a new drug application (NDA) has been submitted for relacorilant for consideration by the FDA.

Early diagnosis of chronic kidney disease (CKD) can help optimize treatment and manage the disease to prevent further decline.

Pharmacy students can provide education, patient advocacy, and medication access.

Pharmacists should be aware of the impacts that anemia in patients being treated for cancer has on daily activities and overall quality of life.

Adherence to thiopurine medications after 6 months of use was 87.9% under direct pharmacist care but 65.7% under general practitioner guidance.

Treatment options may include treating the anemia with blood transfusions, androgen therapy, thalidomide, and other medications.

The potential treatments include ivermectin, methylene blue, glucagon-like peptide-1 receptor agonists, and low-dose naltrexone.

The disparity highlights opportunities for pharmacists to get involved and address health disparities.

Gecacitinib is a novel inhibitor targeting both JAK and ACVR1.

Despite the explosion of public interest in these drugs, ongoing shortages and debates over compounding made access difficult.

Currently available for prescription in the United States, vibegron is now the first and only β3 agonist FDA approved to treat patients living with OAB and being treated for BPH.

Concizumab-mtci is a subcutaneous, monoclonal antibody designed to achieve hemostasis in all hemophilia types.

The medication, glepaglutide, is in development for the treatment of adults with short bowel syndrome with intestinal failure who are dependent on parenteral support.

The approval comes after clinical trial results in which vanzacaftor/tezacaftor/deutivacaftor (Alyftrek; Vertex Pharmaceuticals) demonstrated superiority compared with elexacaftor/tezacaftor/ivacaftor and ivacaftor (Trikafta; Vertex Pharmaceuticals).

Vanzacaftor/tezacaftor/deutivacaftor (Alyftek) also received approval for the treatment of cystic fibrosis in people 6 years and older who have at least 1 F508del mutation.

Setmelanotide is indicated to reduce excess body weight and maintain weight reduction long-term for patients with syndromic or monogenic obesity due to Bardet-Biedl syndrome.

Compounding pharmacies have a 60- to 90-day grace period to complete production as it continues to monitor supply and demand.

The rare genetic disease is a severe hypertriglyceridemia that can lead to potentially life-threatening acute pancreatitis.

Pharmacy errors can happen due to manual processes, but they can be mitigated through adoption of automated IV workflow technology and comprehensive compounding records.

The tool is designed to address the nocebo effect, which was a concern of prescribers and other health care professionals.

Based on positive results from the HERCULES trial, the new designation will allow for more thorough regulatory review and development of the multiple sclerosis treatment.

The full results will be published in a peer-reviewed journal and presented at a medical meeting next year as the full results are evaluated.

According to the report, 75% of survey participants expect pharmacists to oversee these therapies and 58% expect Medicare will require pharmacist involvement.

The addition of samidorphan can support the antipsychotic efficacy of olanzapine while mitigating associated weight gain.

Fabry disease is a rare lysosomal disorder that causes excessive deposition of lipids in tissues.

The treatment is a type IA prodrug of dexamethasone that targets CD206+ macrophages.

Clinicians' enthusiasm for cell and gene therapies is tempered by practical concerns.

The study also found that HSSPs minimize health costs and provide additional revenue for health systems.

A vast majority of patients achieved a positive clinical response with the combination, with improvements in their ocular condition.

Investigators presented additional data from a clinical trial at the American College of Rheumatology Convergence, demonstrating similar safety for postmenopausal women with osteoporosis.