Oncology

FDA to evaluate luspatercept-aamt (Reblozyl) for the treatment of anemia in adults with non–transfusion dependent β-thalassemia.

FDA approves rituximab (Rituxan) plus chemotherapy for pediatric patients with previously untreated, advanced stage, CD20-positive diffuse large B-cell lymphoma, Burkitt lymphoma, Burkitt-like lymphoma, or mature B-cell acute leukemia.

Ibrutinib in combination with venetoclax shows promise in patients with previously untreated chronic lymphocytic leukemia.

Further, among premenopausal women, those who received chemotherapy had a 40% relative improvement in IDFS compared to those administered endocrine therapy alone.

Oncology pharmacists play a significant role in clinical pathways.

The combination of daratumumab with hyaluronidase (Darzalex Faspro), hyaluronidase-fihj, carfilzomib (Kyprolis), and dexamethasone is indicated for the treatment of adult patients with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy.

The diagnostic tool widens the age group of individuals who can get tested and can be used in conjunction with a mammogram.

Underserved populations with limited access to medical care continue to be disproportionately impacted by certain cancers.

Olaparib was the first PARP inhibitor to be developed and has been the most studied.

Although specialty therapies have the potential to help people live healthier lives, their cost and complexity can create distinct challenges.

Ray Tancredi, RPh, MBA, divisional VP of specialty pharmacy development and brand Rx/vaccine purchasing at Walgreens, provides an analysis and overview of key specialty pharmaceuticals in development.

Survey results may imply that individuals who stop could have more health problems or die from a subsequent heart issue.

According to the researchers, almost half of the caregivers surveyed responded that the people they are caring for rely on them more than ever before, with 94% of respondents indicating that they put the needs of the person they care for above their own during the COVID-19 pandemic.

Besermi is an interferon alfa-2b indicated for the treatment of adults with polycythemia vera.

Mobocertinib is a kinase inhibitor of the epidermal growth factor receptor (EGFR) that irreversibly binds to and inhibits EGFR exon 20 insertion mutations at lower concentrations than wild type (WT) EGFR.

The new sFIS assay may be capable of identifying immune biomarkers indicative of survival chances and treatment effectiveness for patients with ovarian cancer.

Patients with advanced renal cell carcinoma who were given the combination of nivolumab and ipilimumab demonstrated a significantly longer overall survival than those who received sunitinib.

Rituximab-pvvr is indicated for the treatment of adult patients with non-Hodgkin lymphoma, chronic lymphocytic leukemia, and granulomatosis.

Investigators have developed an immunotherapy that is a potential option for children with hard-to-treat brain cancer.

The study’s identification of a network of possible candidate genes to carefully control for mutations could alter the future clinical implementation of CRISPR.

A survey of caregivers and parents of children with cancer shows that nearly one-third expressed hesitancy to vaccinate their youngsters against COVID-19.

Breast cancer found to be the most expensive type of the disease, costing approximately $3.4 billion in the United States.

Social determinants of health can play a significant role in the treatment trajectory and outcomes for patients with cancer because oncology care requires close communication between the patient and clinicians.

Study finds COVID-19 booster shot was extremely beneficial for all patients with cancer, especially those with a blood cancer.

Approximately 40% of patients with stage IV melanoma have brain metastases at diagnosis.

The results of a study showed that non-Hispanic Black patients treated with immunotherapy had a 15% lower risk of death from non–small cell lung cancer than non-Hispanic white patients.

Pertuzumab is indicated for use in combination with trastuzumab and docetaxel for treatment of patients with HER2-positive metastatic breast cancer who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease.

Hodgkin lymphoma is most common in people between 20 and 40 years of age and those over 55 years of age.