CLINICAL ROLE -
Receiving SARS-CoV-2 Booster During Pregnancy May Improve Newborn’s Immune Responses to Virus
A COVID-19 booster dose increased both maternal and cord blood binding and neutralizing antibody levels against virus strains, including Omicron BA.1.
Study Indicates Take-at-Home, Oral Ketamine is an Effective Option for Treatment-Resistant Depression
The daily oral formulation of ketamine, KET01, has the potential to greatly improve the standard treatment practices for treatment-resistant depression, according to investigators.
Early Intervention With Nutrient Supplementation May Be Beneficial to Patients with Alzheimer Disease
Through previous literature, investigators found that intervention with nutritional supplements may help to improve cognitive performance and reduce the severity of memory impairment in adults with Alzheimer disease.
Individuals With Sustained or Increasing Opioid Use Were Older, Had More Comorbidities, Higher Use of Other Drugs
Study investigators suggest that there is a higher prevalence of pain and treatment needs in this small population.
Study Finds Sugar-Sweetened, Artificially Sweetened Beverages Associated With Risk of Liver Cancer, Chronic Liver Disease Mortality
Study authors note that additional research is necessary to confirm findings and identify biological pathways of associations between sweetened beverages and diseases of the liver.
Humira Biosimilar Effective in Treating Moderate to Severe Chronic Plaque Psoriasis
Although SB5 is an effective treatment for plaque psoriasis, it is recommended that patients consider the potential risks and adverse effects.
Study Results Suggest Electrical Communication Between Skin Cells May Initiate Melanoma
Findings may have therapeutic implications because of the potential to target neurotransmitters to treat or prevent melanoma.
Pre-Exposure Prophylaxis Continues to be Effective in Preventing HIV, Certain Populations Face Barriers
Lack of information and access to health care, stigma, discrimination, criminalization, and privacy concerns are among the barriers some groups face when trying to obtain preventative HIV medications.
Higher Count of Mitochondrial DNA Fraction With Breaks Associated With Increased Future Risk of Non-Hodgkin Lymphoma
Although additional studies are needed, findings indicate that mtDNAfb may be a useful biomarker for future risk of non-Hodgkin lymphoma.
Depression, Anxiety Linked to Increased Risk of Developing Lung, Smoking-Related Cancers
Though an association was found between depression and anxiety and lung cancers, there were no connections found to overall, breast, prostate, colorectal, and alcohol-related cancers.
Oncological Biosimilars Shown to Be as Safe as Their Reference Products
Study finds patients with cancer feel reassured that biosimilars provide a safe, adequate, and cost-effective alternative to the pricier reference drug.
Once-Weekly Injections of Icodec Insulin Improves Glycemic Control in Type 2 Diabetes Compared to Once-Daily Alternative
Not only was the glycemic control improved, but those who received once-weekly injections of icodec insulin had spent more time in the target glycemic range compared those who received once-daily injections.
Trial Results Show Oral Orexin Receptor 2 -Selective Agonist Is Effective Over Placebo in Improving Wakefulness, Cataplexy in Patients With Narcolepsy Type 1
Despite the improvements in the patients' symptoms, minor adverse effects including urinary urgency and liver-related issues were reported.
Sleep Disturbance Possible Adverse Effect of Cardiac Disease, New Study Finds
The lowering melatonin levels in patients with heart disease is one example of how heart conditions can influence systems throughout the body.
Imaged-Guided Adaptive Radiation Treatments May Reduce Short-Term Adverse Effects in Patients With Prostate Cancer Compared to Non-Adaptive Treatments
Risks of genitourinary and gastrointestinal toxicity were reduced significantly, but longer follow-up is necessary to examine potential future issues.
Study Indicates Increased Risks of Fatal Heart Attack Due to Combination of Heat Waves, High Fine Particulate Pollution Days
The risk could double if the conditions are met, with deaths more common in women and those aged 80 and older.
Study Confirms Association Between Soft Drink Consumption, Weight Gain in Adolescents
Researchers recommend reducing soft drink consumption and increasing physical activity to begin minimizing this widespread issue.
Early Peanut Introduction Deemed Safe to Prevent Allergy, Some Parents Unaware or Hesitant
With new guidelines surrounding the introduction of peanuts to infants as young as 4 months of age, more work needs to be done to increase awareness among parents and caregivers to prevent peanut allergy at an early age.
Patients Who Self-Report as Recovered From SARS-CoV-2 Present No Cognitive Deficits Following Infection
Further work is necessary to monitor and develop understanding of recovery for individuals with ongoing COVID-19 symptoms.
Study Shows Combining Telehealth With In-Office Visits for Prenatal Care Performs Adequately Compared With In-Office Only
Not only is a combination of in-office visits and telemedicine an effective model of prenatal care, but it can be an alternative to those who face access barriers.
Double-Blind Trial Shows Low-Cost Subcutaneous Version of Ketamine Is Effective Over Placebo in Treating Treatment-Resistant Depression
Generic ketamine could cost as little as $5, which is significantly lower than the $800 per dose for the currently available S-ketamine nasal spray.
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