
Opinion|Videos|October 25, 2024
Evaluating New Data for Transplant-Eligible Patients With NDMM: PERSEUS, IsKia, and GMMG HD7
Key Takeaways
- Phase 3 trials PERSEUS, IsKia, and GMMG HD7 compare triplet and quadruplet regimens in transplant-eligible multiple myeloma patients.
- CD38 antibodies are being integrated into treatment protocols, showing improved outcomes with quadruplet regimens.
Panelists discuss how recent phase 3 trial data from PERSEUS, IsKia, and GMMG HD7 are shaping their approach to induction and consolidation therapy in transplant-eligible newly diagnosed multiple myeloma (NDMM) patients, particularly focusing on the incorporation of CD38 antibodies into upfront treatment regimens and the potential shift from triplet to quadruplet therapies based on these pivotal trial findings.
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Episodes in this series

Video content above is prompted by the following:
- What are your thoughts on the following phase 3 trial data on induction and consolidation therapy in transplant-eligible patients with newly diagnosed multiple myeloma (ie, triplet vs quadruplet regimens)?
- PERSEUS
- IsKia
- GMMG HD7
- (Dr Ali) How are you incorporating recent pivotal trial findings around CD38 antibodies into upfront treatment decisions for transplant-eligible populations (ie, PERSEUS, IsKia, and GMMG HD7)?
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