Pediatrics

Biosimilar use is not linked to an increased risk of treatment failure among pediatric patients with inflammatory bowel disease (IBD).

Admissions to the hospital for fever were reduced in pediatric patients with medium-risk ALL receiving intravenous immunoglobulin, a potentially useful finding to help prevent infections in vulnerable patients.

These new regulatory developments put CUTX-101 on track to become the first FDA-approved treatment for patients with Menkes disease.

This association was also observed in siblings of children with autism spectrum disorder.

Management of acute otitis media in children involves evidence-based antibiotic prescribing.

Over 70% of children and young people with long COVID reported improvements in their symptoms within 24 months of their initial positive SARS-CoV-2 test.

Study results show that the updated BNT162b2 XBB vaccine is effective in preventing hospitalizations or emergency department visits associated with COVID-19 complications.

Factors associated with intravenous immunoglobulin (IVIG)-related adverse events include older age, dehydration, and administration of multiple IVIG infusions.

Setmelanotide is indicated to reduce excess body weight and maintain weight reduction long-term for patients with syndromic or monogenic obesity due to Bardet-Biedl syndrome.

The approval makes remestemcel-L-rknd the first approved mesenchymal stromal cell in the United States.

Clesrovimab would be the first and only single dose immunization indicated for infants regardless of weight, aimed to protect against their first RSV season.

Ultra-processed food consumption fuels the rising rates of childhood obesity, diabetes, and liver disease, highlighting opportunities for pharmacist intervention.

The decision is based on positive results from the CAHtalyst trials, which both met their primary and secondary end points.

The authors note that routine screening in patients with primary ciliary dyskinesia to help identify undiagnosed asthma.

The pumps can now be used to treat pediatric patients who have symptomatic acute decompensated heart failure and cardiogenic shock.

The authors found high exposure to butylparaben and low exposure to 4-nonylphenol during pregnancy were risk factors for asthma development in children at 4 years of age.

Children born moderate to late preterm also showed more behavior difficulties compared with those born early term or later.

The treatment is a type IA prodrug of dexamethasone that targets CD206+ macrophages.

Prevalence increased across all subgroups among children and adolescents, with decreases observed in young adults and elderly populations.

These risks were observed to become higher as gestational age decreased.

E-cigarette manufacturers claim the products aid in smoking cessation for adults without the risk of adolescent usage.

The authors recommend that longer assessments with lengthier interventions should be performed to assess potential benefits.

If approved, the new indications include children 6 years and older with moderate to severe plaque psoriasis and children 5 years and older with active juvenile psoriatic arthritis.

Asthma onset earlier in childhood may be linked to more severe difficulties that could extend to executive function abilities.

Pneumococcal disease incidence decreased in adults after pneumococcal vaccines began to be used in children due to indirect protection, with fewer adults found to carry the bacterium that causes disease.