Gilead has refined the pharmacokinetics of tenofovir disoproxil fumarate (TDF), an anchor drug in several single-tablet medications for HIV-1, to create tenofovir alafenamide (TAF). Phase II results indicate superior renal outcomes and equivalent clinical outcomes with TAF versus TDF.
Among HIV-positive patients, concurrent use of medications is associated with nonadherence to antiretroviral therapy.
An experimental single-tablet regimen for treatment-naïve adults infected with HIV demonstrated non-inferiority to an FDA-approved combination pill in achieving undetectable viral load.
Much higher rate of patients in real world discontinuing high priced treatment than during clinical studies.
Study finds tolerance varies between individuals determined by their genes.
Results of a phase 3 trial demonstrate the effectiveness of simeprevir in combination with ribavirin and peginterferon as a treatment for patients coinfected with HIV and HCV.
Data indicates that a simeprevir-based therapy is efficacious in patients with HIV-1/HCV genotype 1 coinfection.
A recent study published in the journal Hepatology indicates that as many as 11% of baby boomers had a positive test result for presence of anti-HCV antibodies.
Study finds HIV suppression reduces hepatitis C viral replication over time.
Following recent analysis, researchers found that infants who received HIV vaccines showed immune response to the vaccine.
Experts at Johns Hopkins say ability to go off antiviral treatment for an extended period of time is a critical goal.
TIM-family proteins may be able to block a wide range of viral infections.
TIM-family proteins may be able to block a wide range of viral infections.
A protein found in nearly half of African Americans speeds removal of medication from the body.
Study suggests pharmacists are more than qualified to navigate outpatients with HIV through treatment options.
Ceasing treatment may be the only way to determine whether HIV is cured, but doing so carries long-term risks.
Study finds that ceasing treatment may be the only way to determine if the disease is cured, but doing so carries long-term risks.
With the recent approval of new hepatitis C treatments, payers are increasingly concerned with controlling costs in this category through policies that may affect treatment decisions.
Roughly one-third of teen girls' clinicians and almost half of teen boys' clinicians did not recommend HPV vaccination in 2013.
Just 20 or 30 years ago, mention of vitamin supplementation caused many health care professionals to talk about creating "expensive urine." Today, however, vitamin and nutrient supplementation has become an important health care intervention.
Male latex condoms are still the best strategy for reducing the spread of HIV infection.
