Vitamin Supplementation May Improve Blood Glucose Management

Long-term use of dietary supplements may improve C-reactive protein, HDL cholesterol, serum homocysteine, blood pressure, and incidence of diabetes.

Although it's unclear how many people who have diabetes use complementary and alternative medications to lower blood glucose, researchers indicate that this is an ‘emerging trend.’ A number of complementary and alternative medications can potentially lower blood sugar, and many patients look at these substances as more natural than synthetic drugs.

Many vitamins have antioxidant potential that may augment synthetic antihyperglycemic medications. Many researchers believe that diabetes increases blood concentrations of the end products of lipid peroxidation (thiobarbituric acid reactive substances and serum malondialdehyde). This causes stress and increases cell membrane leaking. It can also inactivate membrane-bound enzymes and surface receptors.

The journal Diabetology & Metabolic Syndrome has published a systematic review and meta-analysis of vitamins that have antioxidant potential and their use among patients who have type 2 diabetes mellitus (T2DM). The findings discuss a total of 12 studies that looked at antioxidant outcomes. The vitamins that were studied most often included vitamins B, C, D and E.

Vitamin E was related to significant reduction of blood glucose and glycated hemoglobin compared to placebo. The researchers suggest that vitamin E may reduce damage incurred from free radicals on structural and functional components of cells and vessel walls.

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