Rheumatoid Arthritis

The Pharmacy Times® Rheumatoid Arthritis resource center provides clinical news and articles, coverage from conferences and meetings, links to condition-specific resources, and videos and other content.

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Class of Cancer Drugs May Have Potential as Chronic Obstructive Pulmonary Disease Treatment

The ErbB inhibitors, gefitinib, erbstatin, and tryphostin AG825, inhibit a cell signaling process controlling the death-rate of neutrophils, immune cells, which cause damage to the lungs.

FDA Approves Infliximab-Axxq as Biosimilar to Infliximab

Officials with the FDA have approved Amgen’s infliximab-axxq (Avsola), a new biosimiliar to infliximab (Remicade).

Study Assesses Risk of Infections, Cancer With Interleukin Inhibitors in Rheumatic Disease

It is currently uncertain to what extent interleukin inhibitors may increase the risk of serious infections and cancer in patients being treated for rheumatic diseases.

Upadacitinib Shows Promise for Treating Rheumatoid Arthritis in Certain Patients

The European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) agreed on a positive opinion for AbbVie’s upadacitinib (RINVOQ), according to the company.

New Treatment for Rheumatoid Arthritis Granted FDA Approval

Officials with the FDA have approved AbbVie’s upadacitinib (Rinvoq) 15 mg, once-daily oral Janus kinase (JAK) inhibitor, for the treatment of adults with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response or intolerance to methotrexate (MTX-IR).

FDA Approves Upadacitinib for Moderate-to-Severe Rheumatoid Arthritis

Upadacitinib (Rinvoq, AbbVie) is indicated for adults with moderate-to-severe rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate.

Patients with Rheumatoid Arthritis Achieve Low Disease Activity with Tofacitinib

Tofacitinib shows promising results in adult patients with moderately to severely active rheumatoid arthritis as a monotherapy with or without methotrexate.

Study: Statins Prevent Cardiovascular Events for Rheumatoid Arthritis

Research investigates whether statins are safe and effective for patients with inflammatory conditions, such as rheumatoid arthritis.

FDA: Elevated Risk of Blood Clots in Lungs, Death in RA Patients on Higher Dose Tofacitinib

A 10 mg twice daily dose of tofacitinib (Xeljanz, Xeljanz XR, Pfizer) used in patients with rheumatoid arthritis increased the risk of blood clots in the lungs and death in a safety clinical trial.

FDA Officials Report Increased Risk of Blood Clots in Lungs, Death with Higher Dose Tofacitinib

The higher dose is only approved for patients with ulcerative colitis, and not for RA.

Upadacitinib Granted Priority Review for Moderate-to-Severe Rheumatoid Arthritis

The New Drug Application for upadacitinib is supported by data from the phase 3 SELECT trial program evaluating patients with moderate-to-severe rheumatoid arthritis.

Rheumatoid Arthritis Biosimilar Meets Equivalency Endpoints in Phase 1/3 Trial

Rituximab is approved by the FDA for the treatment of adults with rheumatoid arthritis, non-Hodgkin's lymphoma, chronic lymphocytic leukemia, pemphigus vulgaris, granulomatosis with polyangiitis and microscopic polyangiitis.

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