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compounding HOTLINE
Mr. Erickson is director of professional affairs at Gallipot Inc.
Do you have a formulation for extemporaneouspreparation of prednisolone suspension? I have apediatric patient who cannot tolerate the manufacturedpreparation.
Prednisolone Sodium Phosphate OralSolution #1 (sugar-free, alcohol-free, dye-free)Calculated to make 100 mL
Ingredients:
Prednisolone sodium phosphate 0.135 g
Sorbitol 70% USP 50.0 mL
Sodium saccharin 0.500 g
*Flavor concentrate 1.0 mL
Distilled water USP qs ad 100.0 mL
*Raspberry, strawberry, or cherry.
Supplies:
Balance with weights and weigh paper or weigh boats
Graduated cylinder
Mortar and pestle
Beaker
Stirring rod
Procedure:
- Dissolve the prednisolone sodium phosphate and thesodium saccharin in 40 mL of distilled water.
- Add the sorbitol 70% USP and flavor concentrate to (1)with stirring.
- Add sufficient distilled water to (2) to make 100 mL.
Notes: No claims are made as to the uses, safety, efficacy,or bioavailability of this product.
The formula is for informational purposes only.
E-mail your compounding questions to
linkEmail('compounding','PharmacyTimes.com')
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