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Pharmacy Times, Volume 0, 0

Mr. Erickson is director of professional affairs at Gallipot Inc.

Do you have a formulation for extemporaneouspreparation of prednisolone suspension? I have apediatric patient who cannot tolerate the manufacturedpreparation.

Prednisolone Sodium Phosphate OralSolution #1 (sugar-free, alcohol-free, dye-free)Calculated to make 100 mL

Ingredients:

Prednisolone sodium phosphate 0.135 g

Sorbitol 70% USP 50.0 mL

Sodium saccharin 0.500 g

*Flavor concentrate 1.0 mL

Distilled water USP qs ad 100.0 mL

*Raspberry, strawberry, or cherry.

Supplies:

Balance with weights and weigh paper or weigh boats

Graduated cylinder

Mortar and pestle

Beaker

Stirring rod

Procedure:

  • Dissolve the prednisolone sodium phosphate and thesodium saccharin in 40 mL of distilled water.
  • Add the sorbitol 70% USP and flavor concentrate to (1)with stirring.
  • Add sufficient distilled water to (2) to make 100 mL.

Notes: No claims are made as to the uses, safety, efficacy,or bioavailability of this product.

The formula is for informational purposes only.

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