Latest Conference Articles

Treatment of recently diagnosed patients with type 1 diabetes (T1D) with anti-IL-21 and liraglutide for 54 weeks was found to be safe and resulted in sustained insulin secretion and lower insulin dose.

The DPPOS is the long-term follow-up of the Diabetes Prevention Program (DPP), a multicenter trial conducted from 1996 to 2001 that established the success of either an intensive lifestyle program or treatment with metformin to prevent or delay the development of T2D in individuals who were considered at high risk for developing the disease.

Oral insulin (OI) slows insulin decline in those at high risk for type 1 diabetes (T1D), according to a poster session at the American Diabetes Association’s 80th virtual Scientific Sessions.

There have not been many evaluations of the prevalence of, and factors associated with, use of DSME/S and support programs in newly diagnosed patients with type 2 diabetes (T2D) in Louisiana, according to the study authors.

The slowed metabolic decline among the OI trial participants at highest risk was assessed and defined by the DPT1 Risk Scores over a 6.75 threshold.

The TEDDY study also aims to identify environmental triggers that cause the immune destruction of beta cells.

The results of the study demonstrated that dapagliflozin was able to reduce new-onset diabetes by 32%.

The results of the real-world, observational study were presented by Eli Lilly during the American Diabetes Association's 80th Virtual Scientific Sessions.

Dapagliflozin is typically used as a second line GLM in T2D and often added to metformin.

Managing diabetes in rural areas is difficult due to limited access to specialty care and self-management programs.

Ripretinib is a kinase inhibitor indicated for adults with advanced GIST, approved by the FDA in May 2020.

Apalutamide in combination with ADT prolonged median OS by 14 months and decreased the risk of death by 22%. Further, median OS was significantly longer, with 73.9 months for patients receiving treatment with apalutamide in combination with ADT compared with 59.9 months for patients receiving placebo in combination with ADT.

The recent analysis of VB-111 was a phase 3 potential registration study conducted with 400 patients and 95 sites around the world.

“Providing quality of care in a field of cancer risk, genetics, and prevention revolves around 3 essential interdependent components,” said presenter Erin Wysong Hofstatter, MD.

At the 2020 ASCO Annual Meeting, speaker Leslie R. Ellis, MD, MSHPEd, FACP, discussed the results of studies in a session looking into current research on leukemia, MDS, and allotransplant.

Results of the COVID-19 and Cancer Consortium cohort study were presented during the virtual science program of the 2020 American Society of Clinical Oncology (ASCO) Annual Meeting.

A study found that nurse-led follow-up and mobile health app leads to improved relative dose intensity, patient experiences, hospitalizations and their duration, and the rate of treatment-related grade 3 or higher toxicities.

The presence of ongoing SHM or CSR in the context of CLL may support the functionality of DNA damage repair pathways, with potential relevance to therapeutic strategies.

Osimertinib is a third-generation EGFR tyrosine kinase inhibitor and is approved in the United States for first-line treatment of patients with metastatic NSCLC with tumors that have EGFR mutations (exon 19 deletions or exon 21 L858R mutations).

This study was the first to demonstrate efficacy of front-line treatment in the period after initial chemotherapy.

The results of the new study were presented during the virtual scientific program of the 2020 American Society of Clinical Oncology (ASCO) Annual Meeting.

Daunorubicin and cytarabine liposome for injection is a dual-drug liposomal encapsulation of cytarabine and daunorubicin approved by the FDA and EMA for the treatment of adults with newly diagnosed therapy-related AML or AML with myelodysplasia-related changes.

The recent analysis studied 400 patients with thoracic cancers who received chemotherapy within 3 months of being diagnosed with COVID-19.

At the 2020 American Society of Clinical Oncology Virtual Scientific Program, researchers presented a recent study that is the largest to date analyzing CLL treatment patterns among VHA patients between 2013 and 2018.

Trastuzumab deruxtecan (T-DXd) (Enhertu) demonstrated strong efficacy in a phase 2 trial for treatment of HER2-positive metastatic breast cancer.

Treatment with avelumab (Bavencio) potentially cured 8 of 15 women in a trial with gestational trophoblastic tumors resistant to single-agent chemotherapy.

In 2017 alone, there was an estimated 785 fewer cancer deaths in states that adopted Medicaid expansion.

At 5 years follow up, the data showed that the OS for women on olaparib was 42.1%, while the placebo OS was 33.2%.