Ashley Gallagher is an assistant editor at Pharmacy Times®. She graduated from St. Bonaventure University in 2020 in journalism and mass communications. Previously, she worked as a pharmacy technician for a retail chain.
Gamida Cell Announces Dosing of First Patient for NK Cell Therapy Candidate GDA-201
The company-sponsored phase 1/2 study evaluates a cryopreserved, readily available formulation for the treatment of follicular and diffuse large B cell lymphomas.
Study: 61% of Vaccinated Individuals Over 50 Are Likely to Get Fall COVID-19 Booster
Health care providers’ recommendations will make a difference, results of a new poll from the University of Michigan show.
BMY, 2seventy’s Abecma Demonstrates Positive Results for Treatment of Multiple Myeloma
Topline results from the KarMMa-3 trial show that idecabtagene vicleucel significantly improves progression-free survival vs standard regimens.
Pfizer, Valneva Initiate Phase 3 Study for Investigational Lyme Disease Vaccine Candidate
Approximately 6000 participants aged 5 years and older at 50 sites in different countries are set to received 3 doses of VLA 15 µg or the saline placebo, followed by a booster.
AstraZeneca, Daiichi Sankyo’s Dato-DXd With Merck’s Keytruda Shows Positive Data for NSCLC
The interim analysis of the TROPION-Lung02 trial demonstrate an overall response rate of 37% in individuals who were treated with datopotamab deruxtecan and pembrolizumab.
Study Results Link Menopause Before 40 to Increase in Atrial Fibrillation, Heart Failure
Analysis supports positive lifestyle habits, such as exercising and quitting smoking, investigators say.
Study Results Show 86.6% of Individuals With OUD Do Not Receive Life-Saving Medication
Investigators from NYU’s Grossman School of Medicine sound alarm on treatment gap and suggest ways to remove barriers, as opioid overdoses soar to historic levels.
Health Care Providers Should Counsel Patients on Integrative Medicine Strategies
Study suggests that health care providers should discuss with patients whether they are using any integrative medicine strategies, which ones, and why.
FDA Approves sNDA for Nubeqa With Docetaxel to Treat Hormone-Sensitive Prostate Cancer
The approval is based on results of the phase 3 study, ARASENS, that demonstrated a statistically significant increase in overall survival, the trial’s primary endpoint.
Regeneron’s REGM5678 Combination Shows Positive Results for Prostate Cancer
Preliminary data from the ongoing dose-escalation portion of the clinical trial, show dose-dependent anti-tumor activity when combined with standard-dose Libtayo.
Mayo Clinic Study: Diets Higher in Calcium, Potassium Help Prevent Kidney Stones
Unlike prior recommendations for prevention, which focus on dietary factors associated with first-time stone formulation, the new analysis looks at recurrences.
NIH Updates Hepatitis B Strategic Plan to Focus on Developing Cure
Revised plan incorporates lessons from the COVID-19 pandemic and recent advances in technology, aligning with the Department of Health and Human Services’ roadmap.
Keytruda Plus Lenvima Did Not Meet Primary Endpoints for First-Line uHCC Treatment
The median overall survival of the lenvatinib monotherapy arm is longer than that observed in previous clinical trials evaluating it as a monotherapy for unresectable hepatocellular carcinoma.
Bepirovirsen Reduces Levels of Hepatitis B Surface Antigen, Hepatitis B Virus DNA
The B-Clear study investigated the efficacy and safety of 12- or 24-weeks treatment with bepirovirsen in individuals with chronic hepatitis B.
Study: Green Tea Extract Reduces Blood Sugar Levels, Improves Gut Health
Investigators found that the health risks linked to the condition known as metabolic syndrome could be diminished by green tea’s anti-inflammatory benefits in the gut.
Study: Any Amount of Light While Sleeping Linked to Poorer Health Outcomes
Older individuals who were exposed to any amount of light while sleeping were significantly more likely to be obese, have high blood pressure, and have diabetes.
Study: Black, Hispanic Adolescents Have Lower Vitamin D Levels
A recent study found that 61% of otherwise healthy Black and Hispanic adolescents have low vitamin D levels, which continues to drop with age.
Survey Finds 19% Americans Fear Getting Monkeypox Yet Know Little About Infection
Results also show that nearly half are not sure whether a vaccine exists, and a large majority know that the disease spreads through close contact.
Black Individuals Have Higher Risk of Advanced Vision Loss After Primary Open Angle Glaucoma Diagnosis
Study is the first to use an artificial intelligence algorithm to break down visual field loss in new-onset glaucoma cases among population groups in the United States.
Johns Hopkins University Releases Academic Proposal to Improve Access to PrEP
The effective preventive treatment could reduce HIV rates but needs greater access and affordability, especially among Black and Latino populations, investigators contend.
Study: 88.9% of US Population Lives Within 5 Miles of a Community Pharmacy
Driving distance is not a predictor of accessibility for those who do not have a car or access to public transportation, investigators say.
FDA Accepts BLA for Omidubicel for Individuals Who Need Bone Marrow Transplants
If approved the drug will be the first allogeneic advanced stem cell therapy donor source for patients with blood cancers.
Pfizer, BioNTech Initiate Phase 2 Study of Enhanced COVID-19 mRNA-Based Vaccine
The next-generation vaccine candidate, BNT162b5, consists of RNAs encoding enhanced prefusion spike proteins for the SARS-CoV-2 ancestral strain and an Omicron variant.
Genentech’s Subcutaneous Tecentriq Demonstrates Positive Phase 3 Results for NSCLC
IMscin001 analysis shows non-inferior levels of the cancer immunotherapy in the blood compared with intravenous infusion in individuals with advanced non–small cell lung cancer.
AbbVie Submits Applications to EMA, FDA for Upadacitinib to Treat Crohn Disease
Submissions are based on 3 phase 3 clinical trials showing that the drug achieved the co-primary endpoints of clinical remission and endoscopic response as induction and maintenance treatment.
Treatment of Precancerous Growths Decrease Progression to Anal Cancer in Patients With HIV
Investigators found that treatment of high-grade squamous intraepithelial lesions in patients with HIV reduced anal cancer incidence by approximately 57%.
Rybrevant in Combination with Lazertinib Shows Promise in Non–Small Cell Lung Cancer
The findings of the phase 1b/2 CHRYSALIS-2 cohort will be presented at the International Association for the Study of Lung Cancer 2022 World Conference on Lung Cancer.
Study: Antibody Levels Decrease Within 3 Months After COVID-19 Booster
The immune responses to the Omicron variant waned substantially with neutralizing antibody levels decreasing 2.4- to 5.3-fold by 3 months after the booster dose.
FDA Accepts New Drug Application for Tofersen as Treatment of SOD1-ALS
Currently, there is no treatment targeted for superoxide dismutase 1 amyotrophic lateral sclerosis, which has a life expectancy of 3 to 5 years from time of symptom onset.
Second COVID-19 Booster Dose Improves Efficacy Against Omicron Subvariants
After a second booster dose, efficacy against COVID-19 Omicron subvariants rose to 80% within the first 6 months, according to results of a study by the CDC.
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