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Tardive Dyskinesia Uncovered: Early Detection and Collaborative Management Approaches

Tardive Dyskinesia Uncovered: Early Detection and Collaborative Management Approaches

In this Pharmacy Times Peer Exchange series, expert panelists Stephen Saklad, Melissa Cloyd, Jamie Kneebusch, and Farah Khorassani discuss key updates and clinical insights related to tardive dyskinesia (TD). The discussion focuses on raising awareness of TD as a chronic, irreversible condition, the value of early recognition and routine screening, the broader impact of TD on patients' psychosocial well-being and provider engagement, strategies for initiating and optimizing vesicular monoamine transporter 2 (VMAT2) inhibitor therapy, overcoming payer-related and logistical barriers to treatment, the pharmacist's central role in monitoring and supporting long-term adherence, and the metrics and collaborative care strategies that can help ensure successful, sustained management of TD.

Tardive Dyskinesia Uncovered: Early Detection and Collaborative Management Approaches

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Stephen Saklad, Melissa Cloyd, Jamie Kneebusch, and Farah Khorassani discuss the importance of ongoing provider re-education on TD, noting that many clinicians remain unfamiliar with the condition and its presentation, particularly given that effective VMAT2 inhibitor treatments have only been available since 2017.

The panelists examined how early recognition of TD allows providers to optimize antipsychotic therapy and minimize or eliminate anticholinergic medications before patients progress to higher-burden treatment options such as clozapine.

The panelists examined the valuable role caregivers can play in identifying early TD movements, noting that patients often mask symptoms during office visits but may not do so around loved ones, and that caregiver education through accessible resources, such as sponsored videos, can help them recognize subtle signs