Depression

Patients under the care of psychiatric facilities, particularly those taking antipsychotic and antidepressant medications, face the risk of prolonged QTc intervals.

Individuals treated with esketamine were more likely to reach remission and remain relapse-free at 8 weeks of treatment.

Use of antidepressants and other classes of prescription drugs can increase the risk of driving impairment compared to nonuse, so clinicians and pharmacists should review these risks with older adults.

The use of psilocybin, repeated at a low dose, could offer a new form of treatment for individuals with differing forms of mental disorders.

Ketamine topical cream may alleviate symptoms of PTSD without causing the adverse effects and abuse potential often associated with other forms of ketamine administration.

An overview of antidepressant medications and their indications to inform health care professionals of their wide use and to better understand which antidepressant to recommend based on patient-specific characteristics.

Gepirone hydrochloride ER (Exxua; Fabre-Kramer Pharmaceuticals Inc) is in a new class of antidepressants, making it the first and only approved antidepressant that selectively targets serotonin 1A receptors.

Study findings showed a 10% increase in the proportion of individuals staying home due to COVID-19 policy restrictions being associated with a 0.27 increase in PHQ-9 scores for depression.

To promote positive mental health outcomes, researchers urge for policy interventions that focus on home connectedness, peer friendship, and school climate while avoiding full school closures.

Study results could lead to an FDA approval for MDMA to treat post-traumatic stress disorder by the end of 2023.

With some of the most effective antidepressants containing a black box warning, safe and effective treatment for young adults is hard to come by.

California is possibly on the verge of signing a bill that would decriminalize the personal possession of natural psychedelics for those aged 21 years and older.

Although GLP-1 receptor agonists have shown promise in promoting weight loss, they are prescription medications and should be used under the guidance of health care professionals.

Although findings indicate a relationship between vitamin D and mood disorders, further research is needed to clarify efficacy of specific vitamin D levels, as well as supplement dose and form.

SSRI treatment for postnatal depression brought long-term benefits for mothers and their offspring in the following years after childbirth, study findings showed.

KET01 could successfully treat treatment-resistant depression while limiting adverse effects in the home environment, according to the study.

Researchers sought to find a remedy for the development of treatment-resistant depression in patients whose antidepressant treatment has fluctuated in efficacy.

The daily oral formulation of ketamine, KET01, has the potential to greatly improve the standard treatment practices for treatment-resistant depression, according to investigators.

The study implemented a novel workflow for ambulatory care pharmacists to execute pharmacist-administered depression screenings.

A variety of comorbid mood disorders often accompany this condition, including OCD and PTSD.

Though an association was found between depression and anxiety and lung cancers, there were no connections found to overall, breast, prostate, colorectal, and alcohol-related cancers.

However, the FDA said an application for zuranolone to treat major depressive disorder did not provide substantial evidence of efficacy.

Pharmacists working with patients with mental health conditions are able to optimize medication use and improve adherence.

Major pharmacogenomics organizations continue to recognize the potential relevance of pharmacogenomics for psychiatric medication management, mainly due to its effects on pharmacokinetics.

Generic ketamine could cost as little as $5, which is significantly lower than the $800 per dose for the currently available S-ketamine nasal spray.

Further research and regulatory changes are needed, but psychedelic medicines may be able to treat or even cure mental illness in the future.

The benefits of the survey can stretch beyond assessing the parental acceptability of mental health screenings in children and can suggest areas of optimization in providing these screenings more widely and effectively in the future.

Employees who did frequently use AI systems were more than likely to offer help to fellow employees, though it could have been a response to their loneliness.

Several workplace risk factors, including safety concerns going unaddressed, predicted suicidal thoughts.

Depression can affect the trajectory of treatment and associated outcomes.