Oncology

Moxetumomab pasudotox is a nonchemotherapeutic drug that could become the standard of care for patients with relapsed/refractory hairy cell leukemia.

Durvalumab, an FDA-approved immunotherapy, met its second primary endpoint of overall survival in the phase 3 PACIFIC trial for stage 3 non-small cell lung cancer.

In response to the increasing incidence of colorectal cancer in young and middle-aged individuals, the American Cancer Society has updated its screening recommendations.

The addition of nelarabine (Arranon) to standard chemotherapy provided further benefit for patients with moderate or high risk of disease recurrence.

Matthew Hughes, director of Business Development for the Accreditation Commission for Health Care (ACHC), discusses HIV and oncology distinction programs and how these standards bring patients, physicians, and pharmacists together to align care.

Patients with relapsed/refractory B-cell acute lymphoblastic leukemia (ALL) who were treated with inotuzumab ozogamicin (InO) indicated better quality of life, functioning, and symptom scores compared with patients receiving standard-of-care chemotherapies.

Researchers have identified a gene associated with the body’s circadian rhythm that may play a role in the development of breast cancer.

Two studies assessed prostate specific antigen (PSA) progression in patients treated with apalutamide (Erleada, Janssen) and the association between PSA doubling time and survival.

Researchers compared lung cancer care and outcomes, including patient characteristics, stage of cancer at diagnosis, treatment, and overall survival of patients in the United States and England.

Officials with the FDA alerted health care professionals about reduced efficacy for some patients taking pembrolizumab (Keytruda) and atezolizumab (Tecentriq) for metastatic urothelial cancer in ongoing clinical trials.

Top news of the day from across the health care landscape.

At the National Community Oncology Dispensing Association's (NCODA) 2018 Spring Summit, Julianne Orr, PharmD, from Indiana University Health Simon Cancer Center, discusses the pharmacist's role in managing adherence to oral treatment regimens for patients with cancer.

Although nearly every state has some type of rule governing coverage of oncology drugs, the question that continually pops up is whether these rules matter when it comes to formulary inclusion.

CAR T-cell immunotherapy is being hailed as the fifth pillar of cancer treatment.

Specialty pharmacists need to fully understand capecitabine’s place in colorectal cancer treatment to ensure that it is safely and effectively utilized.

The high-level monitoring required for self-managing patients with cancer becomes a challenge when patients are seen less frequently by their provider.

Market access and health care professionals must work to find the balance to provide solid treatment for cancer without burdening the system to a point of collapse.

Oncology economics is the product of driving forces in the health insurance market that are intrinsic to oncology in managed care and unlikely to change.

There is an ongoing shift toward many cancer types being treated as maintenance diseases, which places a significant financial burden not only on patients, but also payers and providers within the health care industry.

Health care providers—including physicians, oncologists, and specialty pharmacists—must leverage their collective resources and expertise to work together to address adherence on a larger scale. 

Following their approval, anti–PD-1 agents reach a significant proportion of patients within a few months, according to new study findings.

Top news of the day from across the health care landscape.

The recommendation means more men could be screened, now that the recommendation has been upgraded from its existing D recommendation to a grade C recommendation.

Researchers found that women with advanced triple-negative breast cancer who had inherited a BRCA mutation benefited more from the chemotherapy carboplatin than standard treatment.

A new study examines how chemoresistance evolves over time, which could lead to improved patient outcomes and survival.

A dual immune-checkpoint blockade efficiently controlled the development of chronic lymphocytic leukemia by restoring functional antitumor immune response.

The development and uptake of antiretroviral therapy for HIV has reduced the risk of certain cancers were previously prevalent.