Oncology

Obesity-associated cancer burden is shifting toward younger individuals, with more dramatic increases in some populations than others.

The FDA has approved Erleada (apalutamide) for the treatment of metastatic castration-sensitive prostate cancer (mCSPC), based on the results from the Phase 3 TITAN study.

Patients with metastatic colorectal cancer harboring certain non-V600 BRAF mutations may benefit from anti-EGFR treatment.

Hematology and oncology pharmacists discussed patient outreach at a panel during the Hematology/Oncology Pharmacy Association’s (HOPA) annual conference in April.

During a presentation at the recent Community Oncology Alliance Annual Conference in Orlando, Florida, Ray Bailey, RPh, discussed the implications of medical marijuana for patients with cancer.

Despite advances in cancer care, patients typically face obstacles to treatment.

As the cost of treating the disease has risen, so too have the direct medical care expenses that patients pay out of pocket, as commercial insurers increasingly shift the burden of paying for treatment to patients through higher premiums, deductibles, and co-pays.

The FDA approval of pembrolizumab plus lenvatinib for this new indication is the first under a new international collaboration with Australia and Canada.

Study finds association between obesity and a greater burden of symptoms and distress among patients with breast or prostate cancer.

As a nonprofit focused on enhancing patient care. COPA is in a unique position to serve as a noncommercial organization dedicated to addressing community oncology pharmacy issues, all in the sole interest of patient care.

Immunotherapy methods emerged on the oncology market as adoptive cell transfers, specifically chimeric antigen receptor (CAR) T-cell therapies, with clear benefits in hematologic malignancy treatment.

There are currently no FDA-approved targeted therapies to treat metastatic MET exon14 skipping-mutated non-small cell lung cancer (NSCLC), according to the Novartis.

As new specialty products have begun to dominate the developmental pipeline, specialty pharmacy has entered the mainstream of the supply chain to the point where we can arguably refer to much of the channel as “traditional specialty.”

Two separate studies highlighted how high drug costs and requirements for prior authorization can hinder access to cancer treatment and affect outcomes.

Oncologists suggest that substituting nab-paclitaxel instead of paclitaxel prior to surgery may lead to reduced risk of disease recurrence for certain women with breast cancer.

Building on the current understanding of spihingosine 1-phosphate levels in regulating T cell function, researchers found that the inhibition of the lipid can lead to more effective uses of immunotherapy in cancer therapy.

Top news of the day from across the health care landscape.

On February 14, 2018, the FDA approved apalutamide (Erleada) by Janssen Biotech Inc for the treatment of nonmetastatic castration-resistant prostate cancer (NM-CRPC).

Novel treatment approach combines a new immunotherapy with stem cell transplantation.

Older women with breast cancer who have a concurrent mental health condition are more likely to use opioids and have worse survival outcomes.

The effect of oral androgen signaling inhibitor therapies on patients with pre-existing cardiovascular disease may increase the risk of death.

An in-house specialty pharmacy can provide significant financial gain for health systems by preventing revenue from being diverted to outside pharmacies.

The findings showed a potential immune biomarker that may help predict patient response to standard-of-care treatment sorafenib for advanced liver cancer.

The newly approved therapy is equivalent to AstraZeneca Pharmaceuticals’ Faslodex injection, 250mg/5mL.

A recent study demonstrates the clinical benefit from the use of direct-acting antivirals for hepatitis C virus in patients with a history of liver cancer.

Cancers of the lung, breast, prostate, and colon are most common in adults aged 85 years and older.

A phase 3 study evaluated the safety and efficacy of oral paclitaxel versus intravenous paclitaxel monotherapy in patients with metastatic breast cancer.

Aspirin therapy found to improve liver function test results and survival after transarterial embolization for hepatocellular carcinoma.