Luke Halpern, Assistant Editor

The Mylight phase 3 trial confirmed that there was no clinically meaningful differences between aflibercept and its reference biologic, Eylea, for patients with wet macular degeneration.

The combination regimen showed positive progression-free survival results among patients with HER2-positive breast cancer in the phase 3 HER2CLIMB-02 trial, but overall survival data have yet to mature.

Researchers recommended less restrictive policy regarding telepharmacies to improve access to medications and pharmacists, while ultimately improving outcomes and adherence to treatment regimens.

Topics discussed include care workflow, app functionalities, problems and disadvantages, and benefits for HIV experts.

Unexpectedly, a study found that more than 70% of cancer survivors were current drinkers, indicating the need for intervention and strategies to reduce harmful drinking habits.

Intravenous immunoglobulin was found to be the most effective immunotherapy in preventing relapses after treatment with steroids in pediatric patients.

Key study finding shows associations between the beat frequency in the rhythmic stimulus in the frontal left sites of infant brains and pathways related to brain modulation and nucleotide levels.

Prior to this study, anti-platelet factor 4 disorder was thought to be caused by exposure to heparin or autoimmune conditions.

A dose of 900 mg per day of gabapentin prior to spine surgery was associated with the lowest pain score among all studied dosages.

Although not a traditional at-risk group for severe respiratory syncytial virus complications, pregnant patients should be aware of the possibility of infection and be educated on proper prevention procedures.

A panel released recommendations in accordance with decades of a changing landscape in acetaminophen poisoning and due to an absence of agreed upon guidelines in the space.

Prior studies had produced conflicting results on whether the pandemic positively or negatively impacted health care-associated C. difficile infections, yet the results of this current study indicate the pandemic played a limited role.

Unexpectedly, the highest increases in delirium compared to projections were in the 66 to 74 years of age group, which could have important personal and societal repercussions, such as earlier development of dementia.

Despite the low uptake of healthy lifestyle behaviors to achieve 5% weight loss or greater, the probability of weight loss increased among individuals with higher initial BMI.

Gretchen Garofoli, PharmD, an associate professor at the West Virginia School of Pharmacy, discusses the current recommendations for COVID-19, respiratory syncytial virus (RSV), and influenza vaccines and vaccine hesitancy.

Results of phase 3 trials could lead to the approval of remibrutinib to provide more effective and controlled treatment of chronic spontaneous urticaria than H1-antihistamines.

There was no association between the amount of evidence behind a product and the time until Medicare coverage, suggesting issues within the coverage determination process itself.

After repeated treatment with packed red blood cell transfusions, treatment with intravenous immunoglobulin in a child with parvovirus B19 infection successfully resolved the infection and negated the need for further transfusions.

Study shows that as patients with type 2 diabetes lost more teeth, their risk of heart failure grew.

Researchers found an increase in patients with melanoma who experience chronic immune-related adverse effects at 18 months compared to a previous study with a follow-up point of 6 months.

Adding human papillomavirus genotypes to the predictive model had a significantly higher effect in improving accuracy compared to adding epidemiological factors and pelvic examination.

The burden of aging-related comorbidities was higher across every age category in women compared to men, and increased with age.

Study results showed no significant association between those who bite their nails and SARS-CoV-2 infection, in addition to a lower rate of infection for those who wear glasses compared to those who don’t wear glasses.

In addition to the low use of structured surveillance overall, modified CHEST criteria only identified a small portion of patients with subsegmental pulmonary embolism eligible to receive structural surveillance.

Researchers say vitamin D supplementation could be a low-cost and effective avenue for the reduction of insulin resistance and better outcomes in preventing and treating diabetes.

Notably, obesity was not independently associated with pulmonary pressure or decreased right ventricle load stress despite being a condition related to diabetes.

Notably, patients with transthyretin cardiac amyloidosis had higher rates of heart failure hospitalizations, including patients treated with tafamidis.

The affect of an aerobic exercise program was more prevalent in patients with ovarian cancer who had at least 1 symptom of chemotherapy-induced peripheral neuropathy at the beginning of the trial.

Guidelines provide clear recommendation that oral transitional therapy is at least as effective as intravenous-only therapy for the treatment of infective endocarditis.

The risk of death by suicide in soldiers was both directly and indirectly related to traumatic brain injury through confounding mental health diagnoses.