Luke Halpern, Assistant Editor

Prior studies had produced conflicting results on whether the pandemic positively or negatively impacted health care-associated C. difficile infections, yet the results of this current study indicate the pandemic played a limited role.

Unexpectedly, the highest increases in delirium compared to projections were in the 66 to 74 years of age group, which could have important personal and societal repercussions, such as earlier development of dementia.

Despite the low uptake of healthy lifestyle behaviors to achieve 5% weight loss or greater, the probability of weight loss increased among individuals with higher initial BMI.

Gretchen Garofoli, PharmD, an associate professor at the West Virginia School of Pharmacy, discusses the current recommendations for COVID-19, respiratory syncytial virus (RSV), and influenza vaccines and vaccine hesitancy.

Results of phase 3 trials could lead to the approval of remibrutinib to provide more effective and controlled treatment of chronic spontaneous urticaria than H1-antihistamines.

There was no association between the amount of evidence behind a product and the time until Medicare coverage, suggesting issues within the coverage determination process itself.

After repeated treatment with packed red blood cell transfusions, treatment with intravenous immunoglobulin in a child with parvovirus B19 infection successfully resolved the infection and negated the need for further transfusions.

Study shows that as patients with type 2 diabetes lost more teeth, their risk of heart failure grew.

Researchers found an increase in patients with melanoma who experience chronic immune-related adverse effects at 18 months compared to a previous study with a follow-up point of 6 months.

Adding human papillomavirus genotypes to the predictive model had a significantly higher effect in improving accuracy compared to adding epidemiological factors and pelvic examination.

The burden of aging-related comorbidities was higher across every age category in women compared to men, and increased with age.

Study results showed no significant association between those who bite their nails and SARS-CoV-2 infection, in addition to a lower rate of infection for those who wear glasses compared to those who don’t wear glasses.

In addition to the low use of structured surveillance overall, modified CHEST criteria only identified a small portion of patients with subsegmental pulmonary embolism eligible to receive structural surveillance.

Researchers say vitamin D supplementation could be a low-cost and effective avenue for the reduction of insulin resistance and better outcomes in preventing and treating diabetes.

Notably, obesity was not independently associated with pulmonary pressure or decreased right ventricle load stress despite being a condition related to diabetes.

Notably, patients with transthyretin cardiac amyloidosis had higher rates of heart failure hospitalizations, including patients treated with tafamidis.

The affect of an aerobic exercise program was more prevalent in patients with ovarian cancer who had at least 1 symptom of chemotherapy-induced peripheral neuropathy at the beginning of the trial.

Guidelines provide clear recommendation that oral transitional therapy is at least as effective as intravenous-only therapy for the treatment of infective endocarditis.

The risk of death by suicide in soldiers was both directly and indirectly related to traumatic brain injury through confounding mental health diagnoses.

Study findings contrast with previously reported research linking aspirin to the secondary prevention of stroke, and are especially notable for older adults who may be more susceptible to bleeding-inducing events.

Study investigators observed no significant differences in oxygen supplementation, hospitalization, or COVID-19 related death between initiators and non-initiators, though they cautioned more research was needed.

Reduced quality of life was observed in patients with hemophilia who were unemployed, had blood-borne illnesses, or had a high annual bleeding rate.

microRNAs have shown potential to be used as biomarkers for diagnosing and treating different types of cancers, though their application in doing so had yet to be determined.

Investigators found that age and the presence of RNAemia in blood were predictors of mortality in patients with severe COVID-19.

A new study revealed multiple locations across the southeast, including Georgia, Kentucky, and Florida, with areas that had high HIV risk but little-to-no preexposure prophylaxis services in the area.

Investigators identified a specific subgroup of patients with mantle cell lymphoma who were at higher risk by defining a combination of MIPI, Ki-67, and p53/TP53 alternations.

The trial was recommended to continue to analyze event-free survival rates, but current results are encouraging for treating estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer.

If approved, the V116 vaccine would be the first pneumococcal conjugate vaccine specifically designed for adults.

The risk of death from both overall and cardiovascular causes was also reduced in patients who underwent complete revascularization.

It was previously undetermined whether the combination of IVIG and ICI would lead to patient complications or reduced efficacy of the cancer treatment, but 2 successful case reports dispel that belief.