Proton Pump Inhibitors Linked to Non-Specific Gastric Inflammation in Children

June 9, 2014

Children exposed to PPIs for more than 6 weeks are found to have an increased risk of non-specific gastric inflammation.

An increased risk of non-specific gastric inflammation is found in children exposed to PPIs for more than 6 weeks.

Exposure to proton pump inhibitors (PPIs) is associated with non-specific gastric inflammation (NSGI) in children, according to a study published in Pediatric Gastroenterology and Hepatology on January 20, 2014. The risk increases if the patient is exposed to a PPI for a period greater than 6 weeks, and significantly increased after 3 months.

For their study, Eduardo Rosas-Blum and colleagues at the University of Texas reviewed 310 endoscopy and biopsy reports of patients who underwent an esophagogastroduodenoscopy between July 2009 and July 2010.

To read the rest of this article, click here.