Patients with heart failure patients must be evaluated and treated for Iron deficiency and anemia.
Prevalence over 50% in ambulatory patients.
Iron deficiency in heart failure is defined as: ferritin < 100 µg/L or ferritin of 100-299 µg/L with a transferrin saturation <20%.

Explanation:

Iron deficiency:

Should be screened and treated for patients with heart failure.
Heart failure outcomes improve as iron levels improve.
Intravenous iron replacement is needed because oral iron replacement trials do not show benefits.
Risk factors for iron deficiency include female sex, advanced heart failure, higher levels of NTpro BNP and C reactive protein.

Reference