Pharmacy Clinical Pearl of the Day: Granuloma Annulare


Granuloma annulare is a skin condition that is not contagious and usually not painful.

Clinical Pearl of the Day: Granuloma Annulare

Granuloma annulare is a skin condition that causes a raised rash or bumps (lesions) in a ring pattern.


  • The most common type of granuloma annulare affects young adults and usually affects the hands and feet.
  • Minor skin injuries and some drugs may trigger the condition. Granuloma annulare is not contagious and usually not painful, but it can make patients feel self-conscious. If it becomes a long-term, chronic condition, granuloma annulare can cause emotional distress.
  • Treatment may clear the skin gradually, but the lesions tend to come back. Untreated, the condition might last from a few weeks to decades.
  • Symptoms may include localized, generalized, or under the skin.
  • Causes may include animal or insect bites, infections, tuberculin skin test, vaccination, sun exposure, minor skin injuries, or drugs.
  • Treatment includes corticosteroid use, ointments, creams and injections, freezing the area, light therapy, and oral medications such as antibiotics and antimalarial agents.


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