
Publication|Articles|October 16, 2025
Pharmacy Practice in Focus: Oncology
- October 2025
- Volume 7
- Issue 7
Current and Emerging BCMAxCD3 Bispecifics
Author(s)Rebekah R. Dyer, PharmD, BCPS
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In the past 10 years, bispecific antibodies have revolutionized the treatment algorithm for relapsed or refractory multiple myeloma. To date, there are 3 BCMA-directed bispecific antibodies that treat RRMM: teclistamab, elranatamab, and linvoseltamab. Therapy sequence and distinctions among agents are a current clinical conundrum. Ongoing research focuses on drug differences, order of agents, managing resistance, and mitigating adverse effects to improve outcomes in multiple myeloma.
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