Pharmacy Clinical Pearl of the Day: Cold Sore


Cold sores are usually caused by herpes simplex virus type 1 and herpes simplex virus type 2.

Clinical Pearl of the Day: Cold Sore

Cold sores, also called fever blisters, are a common viral infection.


  • Cold sores are tiny, fluid-filled blisters on and around your lips. These blisters are often grouped together in patches.
  • After the blisters break, a scab forms that can last several days.
  • Cold sores usually heal in 2 to 3 weeks without leaving a scar.
  • Cold sores spread from person to person by close contact, such as kissing
  • They're usually caused by herpes simplex virus type 1 and, less commonly, herpes simplex virus type 2.
  • Symptoms include tingling, itching, blisters, oozing, and crusting.
  • Treatment options may include acyclovir (Zovirax), valacyclovir (Valtrex), famciclovir, and penciclovir (Denavir).
  • Other treatment options may include lip balms, applying cold compress, rest, and pain relievers.


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