Pharmacy Clinical Pearl of the Day: Churg-Strauss Syndrome

Author(s):

Churg-Strauss syndrome causes inflammation that can restrict blood flow to organs and tissues.

Clinical Pearl of the Day: Churg-Strauss Syndrome

Churg-Strauss syndrome is a disorder marked by blood vessel inflammation.

Insight:

This inflammation can restrict blood flow to organs and tissues, sometimes permanently damaging them.
This condition is also known as eosinophilic granulomatosis with polyangiitis (EGPA).
Adult-onset asthma is the most common sign of Churg-Strauss syndrome.
Symptoms may include loss of appetite, weight loss, joint and muscle pain, abdominal pain, weakness, fatigue, rash, skin sores, pain, numbness and tingling in the hands and feet.
Complications may include peripheral nerve damage, heart disease, and kidney damage.
Diagnosis may include blood test, imaging tests, and biopsy of the affected tissue.
Treatment may include corticosteroids, such as Prednisone, to reduce inflammation; Mepolizumab (Nucala); and other medications such as azathioprine (Azasan, Imuran), benralizumab (Fasenra), cyclophosphamide, methotrexate (Trexall), and rituximab (Rituxan).

Sources:

churg-strauss syndrome - Google Search