Myfembree is indicated to control heavy menstrual bleeding caused by uterine fibroids in premenopausal women. The treatment should not be taken for more than 24 months. It is not known whether Myfembree is safe and effective for use in children under 18 years of age.

Myfembree contains relugolix, which decreases the amount of estrogen and other hormones that are produced by the ovaries; estradiol, an estrogen) that may lower the risk of bone loss; and norethindrone acetate, a progestin that is necessary when women with a uterus take estrogen.