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Opinion|Videos|January 29, 2025

Monitoring Patients Transitioning From Obeticholic Acid

Panelists discuss how transitioning patients from obeticholic acid to seladelpar or elafibranor requires close monitoring of liver biochemistry, pruritus severity, medication adverse effects, and quality of life measures while providing clear patient education about expected timeline for symptom improvement and potential adjustment periods.

Episodes in this series

Video content above is prompted by the following:

  1. What key monitoring parameters should be prioritized when transitioning a patient from obeticholic acid to either seladelpar or elafibranor, especially during the initial stages of therapy?
  2. How should clinicians counsel patients on the expected changes in symptom management and potential side effects when transitioning from obeticholic acid to another PBC therapy?

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