Publication|Articles|November 11, 2026

Supplements

  • Practical Considerations for Stroke Prevention Across the Continuum

Stroke’s Ripple Effects Reach Families, Workplaces, and Communities

Fact checked by: Tracy Ann Politowicz

The costs to patients, their families, their workplaces, and their communities go well beyond dollars and cents.

The Incidence of Stroke Continues to Rise

About the Author

Troy Trygstad, PharmD, PhD, MBA, is executive director of CPESN USA, a clinically integrated network of more than 3500 participating pharmacies. He received his doctor of pharmacy and master of business administration degrees from Drake University and a doctorate in pharmaceutical outcomes and policy from the University of North Carolina. He has recently served on the boards of directors of the Pharmacy Quality Alliance and the American Pharmacists Association Foundation. He also proudly practiced in community pharmacies across North Carolina for 17 years.

Stroke is the second leading cause of death worldwide and the fourth leading cause in the United States.1,2 Age-adjusted stroke mortality declined 38% from 2000 to 2015 and more than 80% over the past half century.3 However, the incidence of new strokes and of strokes that result in death within a year is growing because of the aging population, particularly as the large baby boomer generation reaches older age.1 Just over 3% of the US population reports a history of stroke.4

The Economic Burden of Stroke

In the United States, the average cost of stroke care after the event is $59,900 per patient per year, including both direct and indirect costs.5 Estimates of the total US economic burden range from the high tens of billions to more than $100 billion, depending on which costs of additional care and lost productivity are included. Roughly one-third of the cost is direct (care delivery), one-third is reduced productivity, and one-third is lost productivity due to death.4

The Societal Burden of Stroke

Strokes affect not only patients but also family members, employers, and the community at large. Stroke can cause significant physical and mental disability, placing a heavy burden on those around the patient. Loss of the ability to perform activities of daily living, along with losses in social function, memory, and connectedness, can create a high emotional burden.

A Strategy Shift Driven by Better Knowledge and Better Treatment

Not many decades ago, clinicians had trouble identifying strokes early in their onset and, once the damage was done, relied largely on observation and supportive care. Today, the emphasis is on the “golden hour” (the critical first hour after stroke symptoms begin, when rapid treatment can best limit brain damage), public service announcements and education on recognizing stroke, and much more sophisticated treatment plans and therapies, both in the acute setting and long after the event.

Prevention and Rehabilitation

With a strong emphasis on preventing both first and recurrent strokes through lifestyle changes and medications, there is ample opportunity for pharmacists to help ensure optimal community health. Poststroke care has also advanced greatly, with more intensive and targeted physical rehabilitation and ongoing therapy.

Pharmacies Are Critical Members of the Care Team

Pharmacies can help shoulder the burden of stroke prevention and care, not only by dispensing therapies but also by spending additional time counseling patients and, when appropriate, their family members on all of their therapies. Pharmacies can also provide adherence packaging or other tools to monitor medication use and reduce barriers to following the prescribed regimen.

Conclusion

The toll of a stroke extends well beyond the hospital stay, rippling through families, workplaces, and communities for years after the event. As the population ages and more individuals live with the effects of stroke, community pharmacies are well positioned to help ease that burden. By supporting prevention, helping patients and caregivers manage complex medication regimens, and serving as an accessible point of contact between other health care visits, pharmacists can address not only the patient’s needs but also the second- and third-tier effects of stroke on those around them.

REFERENCES
  1. GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021;20(10):795-820. doi:10.1016/S1474-4422(21)00252-0
  2. Palaniappan LP, Allen NB, Almarzooq ZI, et al; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Committee. 2026 heart disease and stroke statistics: a report of US and global data from the American Heart Association. Circulation. 2026;153(9):e275-e906. doi:10.1161/CIR.0000000000001412
  3. de Havenon A, Sheth KN. Stroke’s resurgence as a leading cause of death in the United States. Stroke. 2025;56(9):e199-e200. doi:10.1161/STROKEAHA.125.052010
  4. Girotra T, Lekoubou A, Bishu KG, Ovbiagele B. A contemporary and comprehensive analysis of the costs of stroke in the United States. J Neurol Sci. 2020;410:116643. doi:10.1016/j.jns.2019.116643
  5. Strilciuc S, Grad DA, Radu C, et al. The economic burden of stroke: a systematic review of cost of illness studies. J Med Life. 2021;14(5):606-619. doi:10.25122/jml-2021-0361

Articles in this issue


Related to this article