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Opinion|Videos|December 25, 2024

Exploring Second-Line Treatments for PBC

Panelists discuss how some patients with primary biliary cholangitis (PBC) have an inadequate response to ursodeoxycholic acid and require second-line treatments, with options including obeticholic acid, seladelpar, and elafibranor, which improve bile acid homeostasis and reduce inflammation.

Episodes in this series

Video content above is prompted by the following:

  1. How often do patients require second-line treatments for PBC, and what agents are available for second-line management?
  2. How do the mechanisms of action differ between seladelpar, elafibranor, and obeticholic acid?

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