Greenstone LLC has just launched nitroglycerin sublingual tablets, an authorized generic version of Pfizer's Nitrostat.
Greenstone LLC has just launched nitroglycerin sublingual tablets, an authorized generic version of Pfizer’s Nitrostat.
Like its brand name counterpart, the product is available in 100-count bottles containing 0.3 mg, 0.4 mg, and 0.6 mg tablets of nitroglycerin. It also comes as a Convenience Pak of 4 25-count bottles of 0.4 mg tablets. The sublingual tablets should not be crushed, chewed, or swallowed.
Nitroglycerin sublingual tablets are typically prescribed to patients for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease.
One tablet should be dissolved under the tongue or in the buccal pouch at the first sign of an acute anginal attack. The dose may be repeated approximately every 5 minutes until relief is obtained. If chest pain persists after a total of 3 tablets in a 15-minute period, or if the pain is different than is typically experienced, prompt medical attention is recommended. The drug may also be used prophylactically 5 to 10 minutes prior to engaging in activities that might precipitate an acute attack.
If possible, patients should sit down when taking the tablets and use caution when returning to a standing position, as this eliminates the possibility of falling due to lightheadedness or dizziness. The most common adverse reactions associated with the product are vertigo, dizziness, weakness, and palpitation.
Patients who have received an excessive amount of nitroglycerin may develop a strong headache, confusion, or fever. Treatment of an overdose is possible, but invasive monitoring may be necessary.