FDA OKs 2 Fixed Dose HIV Treatments

Article

Officials with the FDA have approved 2 different fixed dose drugs indicated to treat HIV-1: Symfi Lo tablets and Biktarvy.

Officials with the FDA have approved 2 different fixed dose drugs indicated to treat HIV-1: Symfi Lo tablets and Biktarvy.

Symfi Lo tablets are a combination of efavirenz (EFV) 400-mg, lamivudine (3TC) 300-mg, tenofovir disoproxil fumarate (TDF) 300-mg. Biktarvy is a combination of bictegravir, emtricitabine, and tenofovir alafenamide.

Symfi Lo

Symfi Lo is indicated to treat adults and children weighing at least 35 kg who are HIV positive, according to the FDA.

Prior to initiating therapy, the FDA advises health care providers to test patients for hepatitis B virus and obtain estimated creatinine clearance (CrCL), urine glucose, and urine protein.

The recommended dose of Symfi Lo tablets is 1 oral tablet once per day on an empty stomach, preferably before bed, according to an FDA release. The FDA noted that taking the treatment at bedtime may make nervous system symptoms more tolerable.

Biktarvy

Biktarvy is indicated as a complete regimen for patients with HIV-1 who are treatment-naïve or who are virologically suppressed on a stable antiretroviral treatment for at least 3 months, according to the FDA.

The agency noted that this treatment requires the same testing as Symfi Lo prior to administration. Biktarvy is also not recommended for patients with estimated CRCL lower than 30-mL/minute or for those with severe hepatic impairment.

To read more about these approvals, visit SpecialtyPharmacyTimes.com.

Related Videos
Female Pharmacist Holding Tablet PC - Image credit: Tyler Olson | stock.adobe.com
African American male pharmacist using digital tablet during inventory in pharmacy - Image credit: sofiko14 | stock.adobe.com
Young woman using smart phone,Social media concept. - Image credit: Urupong | stock.adobe.com
selling mental health medication to man at pharmacy | Image Credit: Syda Productions - stock.adobe.com
Medicine tablets on counting tray with counting spatula at pharmacy | Image Credit: sutlafk - stock.adobe.com
Concept of health care, pharmaceutical business, drug prices, pharmacy, medicine and economics | Image Credit: Oleg - stock.adobe.com
Image credit: rawpixel.com | stock.adobe.com
Medical team -- Image credit: Flamingo Images | stock.adobe.com
© 2024 MJH Life Sciences

All rights reserved.