Eligibility Factors in Multiple Myeloma Transplant

Opinion
Video

Gabriel Hinojosa, PharmD, BCOP, analyzes eligibility factors and treatment shifts in multiple myeloma care, in addition to discussing autologous stem cell transplant risks and evolving therapy approaches with daratumumab.

This is a video synopsis/summary of an Insights involving Gabriel Hinojosa, PharmD, BCOP.

In a discussion on stem cell transplantation, Hinojosa emphasized the critical factors influencing eligibility for autologous stem cell transplant in patients with multiple myeloma. The myeloablative chemotherapy regimen poses significant risks, and although the procedure enhances response depth and remission duration, it’s not curative. Hinojosa stressed the importance of evaluating patient age, comorbidities, organ function, and social support. Transitioning to the comparison of D-RVd (daratumumab [Dara], lenalidomide, bortezomib, dexamethasone) and RVd in first-line multiple myeloma treatment, Hinojosa highlighted the paradigm shift influenced by the GRIFFIN trial. The addition of a Dara tumor map significantly favored a stringent complete response over RVd alone. Recent PERSEUS trial data confirmed improved progression-free survival with subcutaneous daratumumab combined with RVd induction, prompting a shift toward quadruplet therapy for newly diagnosed, transplant-eligible patients. This evolving approach reflects advancements in optimizing treatment outcomes for patients with multiple myeloma.

This summary was AI-generated and reviewed by Pharmacy Times® editorial staff.

Related Videos
1 KOL is featured in this series.
1 KOL is featured in this series.
1 KOL is featured in this series.
1 KOL is featured in this series.
Collaborative Care Team for Diabetes, Cardiovascular Disease | Image Credit: Production Perig - stock.adobe.com
Video 14 - "Closing Remarks on RSV Vaccinations"
Video 13 - "Understanding RSV Infection Patterns and Seasonal Outbreaks"
Video 12 - "Empowering RSV Patients: Essential Vaccine Education Resources"
Video 11 - "Unmet Needs in Prevention and Management of RSV"
Video 12 - "Collaborative Care: Key Stakeholders in HE Treatment and Recovery"
Related Content
© 2024 MJH Life Sciences

All rights reserved.