Advanced Multiple Myeloma Treatments
Gabriel Hinojosa, PharmD, BCOP, looks beyond frontline regimens in multiple myeloma, and discusses treatment options, adverse events, and complexities in sequencing therapies.
EP: 1.Pharmacists in Multiple Myeloma Care: Essential Roles and Patient Support
EP: 2.Eligibility Factors in Multiple Myeloma Transplant
EP: 3.Multiple Myeloma Care: Pharmacist Team Collaboration
EP: 4.Multiple Myeloma Regimen Comparisons
EP: 5.Pharmacist's Role in Enhancing Multiple Myeloma Care
EP: 6.Choosing Multiple Myeloma Regimens
EP: 7.Pharmacists' Patient Counseling Role
EP: 8.Advanced Multiple Myeloma Treatments
EP: 9.Pharmacist-Led Care Transitions: Best Practices
EP: 10.Multiple Myeloma Challenges and Treatment Evolution
This is a video synopsis/summary of an Insights involving Gabriel Hinojosa, PharmD, BCOP.
Hinojosa explored treatment options beyond DRd (daratumumab, lenalidomide, dexamethasone), VRd (bortezomib, lenalidomide, dexamethasone), and KRd (carfilzomib, lenalidomide, dexamethasone) for patients with multiple myeloma, emphasizing diverse regimens based on patient lifestyles and responses. He discussed new drug approvals, including bispecific T-cell engagers and chimeric antigen receptor (CAR) T-cell therapy, providing breakthroughs for patients with limited options. Sequencing therapies remain a challenge, with limited data guiding choices. Beyond the fourth line, the introduction of therapies targeting BCMA and GPRC5D along with CAR T-cell therapy, adds complexity to treatment decisions. Adverse events in later lines include cytokine release syndrome and immune effector cell-associated neurotoxicity, requiring vigilant monitoring for potentially life-threatening complications. The evolving landscape underscores the need for more data and individualized approaches to optimize outcomes in multiple myeloma.
This summary was AI-generated and reviewed by Pharmacy Times® editorial staff.
