Daily OTC Pearl: Vazalore

Vazalore has been shown to cause fewer stomach-related adverse effects than traditional aspirin.

OTC/Lifestyle Pearl of the Day: Vazalore

Indication: Valazore, a new type of aspirin, is a non-steroidal anti-inflammatory drug approved by the FDA in March 2021 as an OTC product that helps prevent blood clots.


  • Classified as a salicylate.
  • Compared to traditional aspirin, Vazalore has been shown to cause fewer stomach-related adverse effects, such as ulcers and damage to the stomach.
  • Dosing: Coronary artery bypass graft 325 mg once daily (start 6 hours after procedure) for 1 year. Percutaneous transluminal coronary angioplasty 325 mg 2 hours before surgery, then 160 mg–325 mg once daily. Carotid endarterectomy 80 mg once daily to 650 mg twice daily (start before surgery).
  • The higher dose of Vazalore (325 mg) works by blocking certain chemicals in the body that cause pain, fever, and swelling.
  • Caution: Do not take if history of bleeding and speak to the provider before starting the medication.
  • If pregnant, discuss the use of Vazalore with a health care provider first.
  • Available dosage: Caps 81 mg—12, 30; 325 mg—30.


What Are the Differences Between Vazalore and OTC Aspirin? - GoodRx

VAZALORE Dosage & Rx Info | Uses, Side Effects (empr.com)