Daily Medication Pearl: Loteprednol Etabonate (Lotemax)


Lotemax treats post-operative inflammation and pain following ocular surgery.

Medication Pearl of the Day: Loteprednol Etabonate (Lotemax)

Indication: Lotemax is a corticosteroid indicated for the treatment of post-operative inflammation and pain following ocular surgery.


  • Dosing:Apply 1 to 2 drops of Lotemax into the conjunctival sac of the affected eye 4 times daily beginning the day after surgery and continuing throughout the first 2 weeks of the post-operative period.
  • Dosage forms: Lotemax contains 5 mg/g of loteprednol etabonate, as a sterile preserved ophthalmic gel.
  • Adverse events: The most common adverse drug reactions were anterior chamber inflammation (5%), eye pain (2%), and foreign body sensation.
  • Mechanism of action: Corticosteroids inhibit the inflammatory response to a variety of inciting agents and probably delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation.
  • Manufacturer: Bausch & Lamb


Related Videos
Laboratory test tubes and solution with stethoscope background | Image Credit: Shutter2U - stock.adobe.com
Image credit: Andrea Izzotti
Inflation Reduction Act is shown using the text and the US flag - Image credit: Andrii | stock.adobe.com
Pharmacy Interior | Image Credit: Tyler Olson - stock.adobe.com
Male pharmacist selling medications at drugstore to a senior woman customer | Image Credit: Zamrznuti tonovi - stock.adobe.com
Pharmacist assists senior woman in buying medicine in pharmacy - Image credit: Drazen | stock.adobe.com
Pharmacy, medicine and senior woman consulting pharmacist on prescription. Healthcare, shopping and elderly female in consultation with medical worker for medication box, pills or product in store - Image credit: C Daniels/peopleimages.com | stock.adobe.com
Image credit: fidaolga - stock.adobe.com
Pharmacists checking inventory at hospital pharmacy- Image credit: Jacob Lund | stock.adobe.com
Young male pharmacist giving prescription medications to senior female customer in a pharmacy | Image Credit: Zamrznuti tonovi - stock.adobe.com
© 2023 MJH Life Sciences

All rights reserved.