Daily Medication Pearl: Crestor (Rosuvastatin)

Article

Crestor is indicated for the treatment of patients with primary hyperlipidemia and mixed dyslipidemia.

Medication Pearl of the Day: Crestor (Rosuvastatin)

Indication: Crestor is used as an adjunct to diet to reduce elevated total-C, LDL-C, ApoB, non-HDL-C, and TG levels and to increase HDL-C for patients with primary hyperlipidemia and mixed dyslipidemia.

Insight:

  • Dosing time: Crestor can be taken with or without food at any time of day.
  • Dose range: Dosing for Crestor can range from 5 to 40 mg once daily. The 40 mg dose should be used only for patients not reaching their LDL-C goal with 20 mg.
  • Dosage forms: Tablets for Crestor come in dosage forms of 5 mg, 10 mg, 20 mg, and 40 mg.
  • Adverse events (AEs): The most frequent AEs (rate ≥ 2%) are headache, myalgia, abdominal pain, asthenia, and nausea.
  • Mechanism of action: Crestor is a selective and competitive inhibitor of HMG-CoA reductase, which is the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, which is a precursor of cholesterol.
  • Manufacturer: AstraZeneca

Source:

Crestor (rosuvastatin calcium) tablets (fda.gov)

Related Videos
selling mental health medication to man at pharmacy | Image Credit: Syda Productions - stock.adobe.com
Medicine tablets on counting tray with counting spatula at pharmacy | Image Credit: sutlafk - stock.adobe.com
Concept of health care, pharmaceutical business, drug prices, pharmacy, medicine and economics | Image Credit: Oleg - stock.adobe.com
Image credit: rawpixel.com | stock.adobe.com
Medical team -- Image credit: Flamingo Images | stock.adobe.com
© 2024 MJH Life Sciences

All rights reserved.