Daily Medication Pearl: Aggrenox (Aspirin/ER, Dipyridamole)

Aggrenox is indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis.

Medication Pearl of the Day: Aggrenox (Aspirin/ER, Dipyridamole)

Indication: Aggrenox is a combination antiplatelet agent indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis.

Insight:

  • Dosing: One capsule twice daily (morning and evening) with or without food.
  • Dosage forms: Capsule 25 mg aspirin/200 mg extended-release dipyridamole.
  • Adverse events (AEs): The most frequently reported AEs (>10% and greater than placebo) were headache, dyspepsia, abdominal pain, nausea, and diarrhea.
  • Mechanism of action: The antithrombotic action of Aggrenox is the result of the additive antiplatelet effects of dipyridamole and aspirin.
  • Manufacturer: Boehringer Ingelheim

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