Broadly Neutralizing Antibodies Combination May Suppress HIV Without Antiretroviral Therapy

A pair of new papers is fueling hope that a combination of next generation broadly neutralizing antibodies might be able to achieve long-term viral suppression of HIV without the need for a daily antiretroviral pill.

Both articles came out of a collaboration between German scientists and researchers at Rockefeller University in New York. Though the research is based on a small pool of participants, it suggests combining anti-HIV antibodies could help defeat resistance and suppress the virus.

With antiretroviral drugs, researchers have previously found that administering a single therapy is usually ineffective, since the virus quickly develops resistance to the drug. Thus, antiretroviral therapy (ART) is typically administered in multi-drug combinations.

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