compounding HOTLINE

Mr. Erickson is director of professional affairs at Gallipot Inc.

Schamberg's Lotion was commercially availableat one time. We cannot find a source now.

Various formulations have been used. Accordingto Martindale, The Extra Pharmacopoeia, 27th ed:

Zinc oxide

8 g

Menthol

0.25 g

Phenol

0.5 g

Calcium hydroxide solution (lime water)*

46 mL

Olive oil qs ad

100 mL

Suggested Method of Preparation

*Prepare calcium hydroxide solution (saturated) prior touse. Combine 10 g with 1000 mL purified water by shakingwell; allow to stand covered overnight. Filter to remove theexcess. The solution should not contain <0.15% CaOH₂.

• Calculate ingredient amounts required for the preparation.
• Weigh/measure ingredients.
• Dissolve the menthol and the phenol in the olive oil.
• Add calcium hydroxide solution; shake well to form an emulsion.
• Add the zinc oxide, stirring until smooth.
• If emulsion is not achieved and is desired, add 2 to 3 drops of Oleic acid and stir well.

Alternative Formulation, Medicated Emollient Suspension

Menthol

600 mg

Phenol

400 mg

Zinc oxide

20 g

Olive oil qs ad

120 mL

Calcium hydroxide solution (lime water)*

120 mL

(Note that total volume is >240 mL.)

Further modification increased the phenol concentrationconsiderably&#8212;"full-strength" Schamberg's Lotion has phenol4 g.

Package in tight, light-resistant containers. Label: "shakewell" and "external use."

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