Videos

1 expert in this video

An expert discusses how different tyrosine kinase inhibitor (TKI) mechanisms of action, including asciminib’s allosteric binding vs traditional ATP-competitive inhibitors, influence treatment selection based on off-target effects and adverse effect profiles, with patients with advanced-phase chronic myeloid leukemia (CML) requiring second-generation or higher TKIs for faster response rates.

1 expert in this video

An expert discusses how National Comprehensive Cancer Network (NCCN) guidelines recommend first-line chronic myeloid leukemia (CML) treatments, including imatinib, nilotinib, and newer agents, emphasizing the importance of close monitoring through weekly laboratory tests and quantitative polymerase chain reaction testing to track BCR::ABL1 transcript levels and ensure patients meet critical milestones at 3, 6, and 12 months.

Panelists discuss how the progression of undiagnosed or untreated tardive dyskinesia in older adults can severely compromise independence and quality of life, emphasizing the need for early recognition, risk factor management, and a multidisciplinary approach—including pharmacists—to ensure timely, individualized, and balanced treatment.

Panelists discuss how enhancing the management of tardive dyskinesia in older patients involves recognizing subtle clinical signs, addressing mental health stigma, and leveraging the pivotal role of pharmacists in early detection, patient education, and coordinated, compassionate care.

Panelists discuss how advancing chronic graft-vs-host disease (cGVHD) management involves improving steroid response rates, exploring combination therapies, utilizing biomarkers for personalized treatment, and striving for steroid-free first-line options to enhance patient outcomes and reduce long-term adverse effects.

Panelists discuss how collaboration between pharmacists and health care providers is essential for optimizing treatment outcomes in chronic graft-vs-host disease (cGVHD), emphasizing the importance of education, symptom management, and a multidisciplinary approach to ensure comprehensive, patient-tailored care.