CLINICAL ROLE -
A Review of Treatment Options, Guidelines for Heart Failure With Preserved Ejection Fraction
With the release of the 2022 AHA/ACC Guidelines for the Management of Heart Failure, patients with HFpEF now have a wider range of treatment options.
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New Drug Delivery Method Could Replace Injections With Pills
The findings provide an alternative delivery strategy for peptide-based drugs and suggest that such techniques and principles could be applied to a broader range of drugs.
Vitamin D Supplementation Linked to Fewer Cases of Melanoma
In the geographical region of a recent study, data showed melanoma cause high mortality rates in relation to incidence.
Accelerate Time to Specialty Pharmacy Therapy with Digital Options
Digitizing hub processes can create an efficient and effective tech-driven patient access strategy speeding access to lifesaving therapies.
Depression Associated With Lower Medication Adherence Post-Percutaneous Coronary Intervention
Patients with depression were significantly less likely to have adequate 12-month adherence to antiplatelets, β-blockers, and statins than those without depression.
Study Evaluates Impact of CDI on Patients With Cystic Fibrosis
Patients with cystic fibrosis are typically administered antibiotics throughout their lives, which can increase the risk for C difficile infections.
Respiratory Syncytial Virus Vaccine Candidates Create Hope to Limit Global Infections
There are currently 33 RSV prevention candidates in clinical development using 6 different approaches.
Wearable Device Accurately Tracks Heart Failure Progression
Approximately half of patients with heart failure do not require an implantable monitoring device or do not qualify for thoracic monitoring.
FDA Approves FoundationOne Liquid CDx to Identify Genomic Profile in NSCLC
The biopsy test is the first companion diagnostic approved for entrectinib for individuals who do not have an available tissue sample.
Report Identifies 15 Key Drugs Predicted to Achieve Blockbuster Status by 2027
The report highlights the growth of personalized medicines with improved efficacy for rare, previously untreatable diseases.
Former CDC Director Discusses Public Health's Impact on National Policy
The first episode of the Public Health Matters Video Series features Tom Frieden, MPH, MD, who discusses his background and influence on public health and national policy.
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Use of Telehealth Services for Mental Health Dramatically Increased in 2020, Offsetting Rapid Decline of In-Person Care
Individuals in metropolitan counties used mental health services more than individuals in rural counties.
Pain Management in Patients With Opioid Use Disorders
The chronic and excessive use of opioids has been associated with a wide range of psychosocial effects on the patient.
Differentiating Features of Atypical Hepatocellular Carcinoma vs Intrahepatic Mass-Forming Cholangiocarcinoma in Contrast-Enhanced MRI
Distinguishing between atypical hepatocellular carcinomas and intrahepatic cholangiocarcinoma can be difficult, but researchers identified several reliable MRI features to assist in differentiation.
Disparity Among Black, White Adults With Uncontrolled Blood Pressure
Black patients aged 18 to 49 years showed a greater association with uncontrolled blood pressure while on an antihypertensive medication.
Dapagliflozin Shows Safety, Efficacy in Heart Failure with Improved Ejection Fraction
A prespecified analysis of the DELIVER trial found the SGLT2 inhibitor dapagliflozin to benefit patients in a patient population previously excluded from heart failure outcomes trials.
FDA Grants Priority Review to Glofitamab for Relapsed/Refractory Large B-Cell Lymphoma
If approved, glofitamab will treat the most aggressive type of non-Hodgkin lymphoma.
Hybrid Immunization Can Provide 90% Protection Against Omicron BA.5 Variant
Relative risk calculations show that vaccinated individuals infected with the first Omicron subvariants of COVID-19 could have protection that lasts nearly 3 seasons.
FDA Grants EUA to Mpox PCR Assay Test
There have been more than 80,000 monkeypox cases reported worldwide.
Generous Parental Leave Protects Against Poorer Mental Health, Study Results Show
Mothers, in particular, benefit when they are given longer leaves and policies that offer incentives or wage replacement, analysis indicates.
FDA Grants Accelerated Approval to Lecanemab for Early Stage Alzheimer Disease
Lecanemab (Lequembi) approved to treat mild cognitive impairment or mild dementia associated with Alzheimer disease.
Study: Common Fatty Acid Contributes to Pain, Temperature Sensitivity in Psoriasis Plaques
Results show an association between linoleic acid, found in nuts, seeds, and vegetable oils, and increased hypersensitivity in psoriatic lesions.
Clinical Overview: Cardiovascular Implantable Electronic Devices
Pharmacists need to ensure anticoagulants are held appropriately before and after surgery to prevent complications from for CIED infections.
FDA Approves Briumvi for Relapsing Multiple Sclerosis
Ublituximab-xiiy from TG Therapeutics Inc is the first anti-CD20 monoclonal antibody approved for individuals with RMS that is administered as a 1-hour infusion after the starting dose.
FDA Grants Breakthrough Therapy Designation to Adagrasib, Cetuximab Combination
The findings show promising clinical activity and a favorable tolerability profile in the treatment of KRASG12C-mutated advanced colorectal cancer.
FDA Accepts for Review BLA for Pfizer’s Pentavalent Meningococcal Vaccine Candidate
MenABCWY combines components of 2 vaccines, which help protect against serogroups that cause most cases of the invasive disease.
More Research Is Needed to Improve MGCS Management, Review Says
A better understanding of the pathogenesis of monoclonal gammopathy of clinical significance would help guide clinicians treating the complex condition.
AI Can Map Entire Patient Journey in Precision Oncology, From Clinical Trial Matching to Drug Matching
This technology could facilitate equal access to value-based pathways in oncology care and optimize the individual treatment approach.
Pharmacy Focus - Advancing Practice in Pharmacy
Deeb Eid, PharmD, RPh, regulatory affairs advisor in Pharmacy at CVS Health, discusses the future and advancing practice of pharmacy.
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Perinatal Women’s Views of Pharmacist-Delivered Perinatal Depression Screening
Pharmacists are ideally positioned within communities to identify patients struggling with perinatal depression.