Following a review of the latest interim data released by AstraZeneca on its US phase 3 clinical trial assessing the 2-dose AZD1222 COVID-19 vaccine, the Data and Safety Monitoring Board (DSMB) expressed concern at the inclusion of what may have been outdated data.
Phase 3 clinical testing of a plant-derived COVID-19 vaccine candidate in combination with a pandemic adjuvant commenced following approval to proceed with participant enrollment from regulatory authorities in both Canada and the United States.
Investigators found a statistically significant improvement in both overall survival and progression-free survival for patients who received pembrolizumab with chemotherapy.
Intranasal administration of virucidal and antiviral therapies may provide added clinical benefit by decreasing viral activity in the nasal pathway, preventing COVID-19 transmission and managing disease severity.
Low doses of propylparaben–a chemical preservative found in food, drugs, and cosmetics–can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer normally conveyed by pregnancy hormones.
The IGCS Mentorship and Training Program seeks to provide training and education to regions without formal training programs in gynecologic oncology.
Theresa Mallick-Searle, MS, RN-BC, ANP-BC, shares her perspective on the new labeling requirements put forth by the FDA for opioids in regard to naloxone.
Joshua Lynch, DO, EMT-P, FAAEM, FACEP, highlight risks he has seen in the community for unintended users as well as patients for accidental opioid overdose.
This was the first genome-wide association study of skin pigmentation in African Americans, according to the study authors.
Clinicians have been searching for accurate, reliable, non-invasive diagnostic tools to differentiate early stage, less dangerous, and more treatable stages of the disease from the aggressive, high-grade and likely-to-spread forms.
The independent data safety monitoring board conducted a specific review of thrombotic events related to AstraZeneca’s COVID-19 vaccine and found no increased risk.
Black adults living in rural areas of the United States have experienced higher mortality rates due to diabetes, hypertension, heart disease, and stroke compared to white adults over the past 20 years, according to a research letter published in the Journal of the American College of Cardiology.
Caroline Carney, MD, MSc, FAPM, CPHQ, CMO of Magellan Health, discusses how pharmacists can be first line in noticing changes in patients’ cognitive functioning.
The first participants were dosed in the phase 2/3 KidCOVE study investigating vaccine candidate mRNA-1273 against COVID-19 in children aged 6 months to less than 12 years of age.
This week on Pharmacy Times, there are a number of important topics that will be covered and posted throughout the week.
The findings reveal a unique mechanism for C.diff survival in the human gut and suggest novel strategies for weakening its defenses, according to the study authors.
The research demonstrates that the coronavirus enzyme PLpro physically interacts with the receptor MDA5 and inhibits the ISGylation process.
According to study results presented at the SGO meeting, biopsies showed no signs of cancer or precancer in two-thirds of 165 women with stage I endometrial cancer or atypical endometrial hyperplasia, 6 months after insertion of the hormonal IUD.
This week is National Brain Awareness Week, so Pharmacy Times® interviewed Caroline Carney, MD, MSc, FAPM, CPHQ, CMO of Magellan Health, on some of the issues surrounding the contemporary understanding of mental health and brain health.
In a recent interview with Pharmacy Times, Raj Desai, PharmD, MBA, discussed a recent COVID-19 vaccination event at Houston Methodist Sugar Land Hospital, where he is the director of pharmacy.
Nine in 10 patients with multiple sclerosis who received the medication did not have worsening of 3-month disability, and ponesimod showed a numerical benefit in delaying disability progression.
Community pharmacists have an essential role to play during this phase of the crisis that could further entrench them as the epicenter of care in the communities they serve.
One recent study found COVID-19 antibodies in all 20 pregnant women and their newborns.
Study findings contradict a long-standing hypothesis that held the pancreas increases insulin production because the cells have already become insulin-resistant and blood sugar rises as a result.
How much does this federal program affect the success of the health care parties involved?
The Pharmacy Times® Pharmacy Focus podcast provides the latest industry news and information, thought-leader insights, clinical updates, patient counseling tools, and innovative solutions for the everyday practice and business of pharmacy.
Language barriers can present a major obstacle to patient involvement in cancer care, although clinicians recommended several potential strategies to help patients who speak different languages.
The study also found that women with chest pain were more likely than men to wait more than 12 hours before seeking medical help.
In the 4th century BCE, Hippocrates, the founding father of medicine, established that the best cure for hemorrhoids was through the application of the curative properties of fire.
Pharmacy Times® interviewed George Rafferty, president of corporate partnerships at AmerisourceBergen, on how large retail pharmacies have been impacted by and been able to respond to the challenges of the COVID-19 pandemic.
