Neurology

Major pharmacogenomics organizations continue to recognize the potential relevance of pharmacogenomics for psychiatric medication management, mainly due to its effects on pharmacokinetics.

Idiopathic intracranial hypertension was previously considered a rare condition, however, its prevalence is increasing in parallel with obesity in patient populations.

Mobile apps can help consumers acquire medications, but few help with adherence beyond automatic refills or medication synchronization.

Participants were able to stop treatment after achieving amyloid plaque clearance and experience lasting results.

Study suggests supplemental oxygen may improve cognitive functions that are vital in motor learning, which can be important for people with neurological conditions or trauma.

Studies consistently demonstrate the pivotal involvement of neuropeptide calcitonin gene related peptide release in migraine onset.

Lecanemab-irmb is the first amyloid beta-directed antibody to be converted from an accelerated approval to a traditional approval for the treatment of Alzheimer disease.

The safety and efficacy of long-term benzodiazepine use beyond the recommended timeframe is not well understood.

The blood pressure drug could provide relief for veterans and service members suffering from traumatic brain injuries.

Despite prior studies showing less brain injury biomarkers in patients with targeted mild hypercapnia, findings from a new trial suggest it does not improve neurological outcomes at 6 months.

Galcanezumab-gnlm (Emgality; Eli Lilly and Company) did not demonstrate superiority to rimegepant orally disintegrating tablet (Nurtec ODT) on the percentage of individuals achieving a 50% or greater reduction in monthly migraine headache days.

Notably, donor hearts from those who underwent circulatory death were able to be preserved and analyzed in situ.

Access, diagnosis, and treatment for BIPOC patients suffering from migraines is yet another unflattering reflection of the lack of health equity in the United States.

As part of the approval condition, the FDA is requiring Sarepta Therapeutics to complete a clinical study to confirm the drug’s benefit in motor and physical functions.

Migraines can be a primary diagnosis or a symptom of an underlying medical or psychological condition.

Leqembi is an intravenous injection for the treatment of Alzheimer disease.

Standard prediction models that assess an individual’s risk of developing dementia and how to prevent it are limited in their ability to do so, showing high error rates and a higher chance of receiving a false-positive result, according to a recent study.

Heidi Finnes, PharmD, BCOP, FHOPA, addresses how the study data may impact the treatment of IDH1/2 mutating gliomas going forward.

Study evaluates the interaction between excessive salt intake and hypertension, cognitive dysfunction, and dementia.

Neuromyelitis optica spectrum disorder is an autoimmune disease characterized by severe attacks of optic neuritis and/or myelitis, leading to possible visual loss, paralysis, cognitive impairment, sensory deficits, bladder dysfunction, and even mortality.

Having more severe sleep apneas was associated with having lower brain volume in the medial temporal lobe area of the brain, which could suggest loss of brain cells.

Current standard of care gives 2 poor options to patients, neither of which cure grade 2 gliomas.

Pediatric drug development, which has a complex background and history, has fundamental catches based around how children are defined in the context of clinical studies.

Although an established standard of care for migraine prophylaxis exists, the current protocol is not without significant shortcomings.

Long-term data show that early treatment with ofatumumab decreased confirmed disability worsening in nearly all study patients with relapsing multiple sclerosis.